Anti-alpha-actinin-4 Anticorpo G-4é um anticorpo monoclonal produzido em camundongo IgG2a κ α-actinin-4 anticorpo, citado em 3 publicações, fornecido em 200 µg/ml
Produzido contra aminoácidos 610-660 mapeamento dentro de uma região interna deα-actinin-4 de human origem
Anti-alpha-actinin-4 Anticorpo (G-4) é recomendado para a detecção de α-actinin-4 de mouse, rat e human origem em WB, IP, IF, IHC(P) e ELISA
Anti-alpha-actinin-4 Antibody (G-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de α-actinin-4 (G-4): sc-390205.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) is the preferred secondary detection reagent for α-actinin-4 Antibody (G-4) for WB and IHC(P) applications. This reagent is now offered in a bundle with α-actinin-4 Antibody (G-4) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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α-actinin-4 Antibody (G-4) is a high quality monoclonal alpha-actinin-4 antibody (also designated ACTN4 antibody, Alpha-actinin-4 antibody or Non-muscle alpha-actinin 4 antibody) suitable for the detection of the alpha-actinin-4 protein of mouse, rat and human origin. α-actinin-4 Antibody (G-4) is available as both the non-conjugated anti-alpha-actinin-4 antibody form, as well as multiple conjugated forms of anti-alpha-actinin-4 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and α-actinins. There are four tissue-specific α-actinins, namely α-actinin-1, α-actinin-2, α-actinin-3 and α-actinin-4, which are localized to muscle and non-muscle cells, including skeletal, cardiac and smooth muscle cells, as well as within the cytoskeleton. Each α-actinin protein contains one Actin-binding domain, two calponin-homology domains, two EF-hand domains and four spectrin repeats, through which they function as bundling proteins that can cross-link F-Actin, thus anchoring Actin to a variety of intracellular structures. Defects in the gene encoding α-actinin-4 are the cause of focal segmental glomerulosclerosis 1 (FSGS1), a common renal lesion characterized by decreasing kidney function and, ultimately, renal failure.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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