Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4G, eIF4E, and eIF4A. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E binds to the mRNA "cap" during an early step in the initiation of protein synthesis. eIF4E-Transporter (4E-T) is a nucleocytoplasmic protein that faciliates the nuclear import of eIF4E by regulating the formation of a complex between the eIF4E and the importin αβ pathway. This interaction between 4E-T and elF4E occurs through a conserved binding site. In addition to this binding site for eIF4E, 4E-T contains a bipartite nuclear localization signal and two leucine-rich nuclear export signals. The gene encoding for 4E-T maps to human chromosome 22q11.2.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.