SPRR2B activators belong to a class of chemical compounds designed to interact with and modulate the activity of the SPRR2B protein. SPRR2B, or Small Proline-Rich Protein 2B, is a member of the small proline-rich protein family, which is characterized by their high proline content and their involvement in various cellular processes such as differentiation, wound healing, and barrier function. SPRR2B, specifically, is primarily expressed in epithelial tissues, including the skin, oral mucosa, and esophagus, where it is believed to play crucial roles in maintaining tissue integrity and providing protection against environmental stressors. The designation activators suggests that these compounds engage with SPRR2B to modulate its activity, potentially leading to downstream effects on cellular physiology and tissue homeostasis.
Research into SPRR2B activators involves elucidating the molecular mechanisms underlying their interaction with the SPRR2B protein and how this interaction influences cellular processes, particularly in epithelial tissues. Understanding the pharmacological properties of these compounds is vital for deciphering how they impact SPRR2B activity and potentially affect epithelial barrier function, wound healing, and other physiological processes. By unraveling the biological functions and regulatory mechanisms of SPRR2B, researchers aim to deepen our understanding of epithelial biology and may uncover novel insights into the molecular pathways underlying tissue integrity and repair. Continued investigation into SPRR2B activators holds promise for advancing our knowledge of epithelial physiology and may provide insights into new strategies for manipulating tissue homeostasis in experimental contexts.
| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
O ácido trans-retinóico, um metabolito da vitamina A, influencia a diferenciação das células da pele e pode regular positivamente o SPRR2B como parte da resposta da pele à sinalização retinoide. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
A forma ativa da vitamina D, o calcitriol, modula o crescimento e a diferenciação das células da pele, influenciando potencialmente a expressão de SPRR2B nas células epidérmicas. | ||||||
Tazarotene | 118292-40-3 | sc-220193 | 10 mg | $103.00 | ||
O tazaroteno pode afetar a proliferação e diferenciação das células da pele, possivelmente regulando positivamente o SPRR2B. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
O ácido salicílico, um beta-hidroxiácido utilizado no tratamento do acne e da psoríase, poderia influenciar a expressão de SPRR2B através dos seus efeitos na renovação das células da pele. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Uma forma de vitamina B3, a nicotinamida tem propriedades anti-inflamatórias e pode modular a expressão de SPRR2B no contexto da reparação e manutenção da barreira cutânea. | ||||||
Hyaluronic acid | 9004-61-9 | sc-337865 | 10 mg | $204.00 | ||
O ácido hialurónico pode influenciar a expressão de SPRR2B, melhorando a função de barreira e a reparação da pele. | ||||||
Glycerol | 56-81-5 | sc-29095A sc-29095 | 100 ml 1 L | $55.00 $150.00 | 12 | |
O glicerol atrai a humidade para a pele, afectando potencialmente a expressão de SPRR2B no processo de hidratação e reparação da pele. | ||||||