Date published: 2025-10-30

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Slfn1 Ativadores

Slfn1," or Schlafen family member 1, is a gene that plays a role in the immune response and cellular growth regulation. It belongs to the Schlafen (Slfn) gene family, which is known for its involvement in the regulation of cell proliferation, differentiation, and immune system functions.The Schlafen genes are characterized by their expression in response to various immunological stimuli. Specifically, Slfn1 has been observed to be upregulated in response to interferons, which are cytokines that play a critical role in the immune response, particularly in antiviral defense. This upregulation suggests that Slfn1 is involved in the cellular response to viral infections.

The protein encoded by the Slfn1 gene has been implicated in the regulation of cell growth and the cell cycle. This regulation is crucial for maintaining normal cellular functions and for preventing abnormal cell proliferation, which is a hallmark of cancer. Research has indicated that Slfn1 may have a role in inhibiting the growth of certain types of cancer cells, though the exact mechanisms are not fully understood.

VEJA TAMBÉM

Nome do ProdutoCAS #Numero de CatalogoQuantidadePrecoUso e aplicacaoNOTAS

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$62.00
$90.00
$299.00
$475.00
$1015.00
$2099.00
69
(5)

Um imunossupressor que pode afetar a função das células imunitárias, com potencial impacto no SLFN1.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

A rapamicina, um inibidor da mTOR, pode influenciar a SLFN1 ao afetar a proliferação e a sobrevivência celular.

Ruxolitinib

941678-49-5sc-364729
sc-364729A
sc-364729A-CW
5 mg
25 mg
25 mg
$246.00
$490.00
$536.00
16
(1)

Os inibidores da JAK podem modular a sinalização das citocinas, afectando potencialmente o papel da SLFN1 na função das células imunitárias.

Azathioprine

446-86-6sc-210853D
sc-210853
sc-210853A
sc-210853B
sc-210853C
500 mg
1 g
2 g
5 g
10 g
$199.00
$173.00
$342.00
$495.00
$690.00
1
(1)

Um fármaco imunossupressor que pode influenciar indiretamente a atividade de SLFN1 através dos seus efeitos nas células imunitárias.

Prednisone

53-03-2sc-205816
sc-205816A
sc-205816B
1 g
5 g
25 g
$41.00
$133.00
$663.00
2
(1)

Como corticosteroide, a Prednisona afecta as respostas imunitárias, o que pode influenciar indiretamente a SLFN1.

Thalidomide

50-35-1sc-201445
sc-201445A
100 mg
500 mg
$109.00
$350.00
8
(0)

Conhecida pelos seus efeitos imunomoduladores, a talidomida pode afetar indiretamente a atividade do SLFN1.

Mycophenolate mofetil

128794-94-5sc-200971
sc-200971A
20 mg
100 mg
$36.00
$107.00
1
(1)

Um imunossupressor que pode ter uma influência indireta no SLFN1 através da sua ação nos linfócitos.