Date published: 2025-9-11

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LOC439950 Ativadores

The term LOC439950 Activators refers to a class of chemical agents that specifically interact with and increase the activity of the protein product of the gene designated as LOC439950. This alphanumeric label indicates a locus or a specific position within the human genome that has been identified but whose gene product and associated functions may not be fully characterized. The 'LOC' prefix is commonly assigned to loci that are thought to represent putative protein-coding regions within the genome, and the succeeding number serves as a unique identifier for researchers to reference this specific genomic segment. Activators in this context are molecules that enhance the biological activity of the protein encoded by LOC439950. They may do so through various mechanisms, such as increasing the transcriptional rates of the gene, stabilizing the protein product to prolong its cellular lifespan, or facilitating its interactions with other proteins or biochemical pathways within the cell.

The discovery and development of LOC439950 activators would involve a multi-disciplinary approach, initially focusing on the characterization of the LOC439950 protein. If the protein's structure could be resolved through methods such as X-ray crystallography, NMR spectroscopy, or cryo-electron microscopy, this would provide invaluable insights into potential binding sites for small molecule activators. These activators would be designed to bind to the protein with high specificity, thereby enhancing its natural activity without disrupting other cellular mechanisms. Subsequent steps would include the synthesis of a diverse chemical library, with each compound designed to interact with the identified binding sites on the LOC439950 protein. Sophisticated high-throughput screening techniques would then be employed to test these compounds for their ability to modulate the protein's activity. Hits from this screening would be subjected to an iterative process of chemical modification to fine-tune their properties, such as binding affinity, specificity, and the ability to positively modulate the LOC439950 protein's activity. Through this cycle of design, testing, and refinement, effective LOC439950 activators would be developed, each uniquely crafted to engage with the protein product of the LOC439950 gene and elevate its functional state within the cellular context.

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Nome do ProdutoCAS #Numero de CatalogoQuantidadePrecoUso e aplicacaoNOTAS

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Pode influenciar a via de sinalização Wnt, que pode alterar a transcrição de genes e afetar potencialmente os níveis de ncRNAs, incluindo RNAs antisense.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

Um inibidor da DNA metiltransferase que pode causar desmetilação do DNA, o que pode ativar a transcrição de certos RNAs não codificantes.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

Um inibidor não-nucleosídeo da DNA metiltransferase que pode levar à desmetilação do DNA e potencialmente aumentar a transcrição de ncRNAs.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Um inibidor da histona desacetilase que pode alterar a estrutura da cromatina, aumentando potencialmente a expressão de ncRNAs, incluindo transcrições antisense.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Um composto derivado de plantas que pode modular muitas vias de sinalização e influenciar potencialmente a expressão de ncRNA através dos seus efeitos epigenéticos.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Demonstrou ter um amplo impacto na expressão genética, possivelmente afectando a transcrição de ncRNAs devido às suas capacidades de modulação epigenética.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
18
(3)

Como inibidor da histona desacetilase, pode alterar a dinâmica da cromatina e afetar potencialmente a expressão de ncRNAs.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

Um composto encontrado em vegetais crucíferos que pode afetar a expressão genética e pode influenciar os níveis de ncRNA através de mecanismos epigenéticos.

(±)-Methyl Jasmonate

39924-52-2sc-205386
sc-205386A
sc-205386B
sc-205386C
sc-205386D
sc-205386E
sc-205386F
1 g
5 g
10 g
50 g
100 g
500 g
1 kg
$35.00
$103.00
$200.00
$873.00
$1638.00
$6942.00
$12246.00
(1)

Uma hormona vegetal que pode influenciar uma vasta gama de padrões de expressão génica, incluindo potencialmente a transcrição de RNAs antisense.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Outro inibidor da DNA metiltransferase que pode levar à hipometilação do DNA e pode afetar a transcrição de ncRNAs.