Date published: 2025-10-30

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IBA2 Ativadores

IBA2 is a protein encoded by the PLEKHM1P gene in humans. This gene is also known as "IBA2 pseudogene," indicating that it is a non-functional copy of a gene. Pseudogenes arise from the duplication or mutation of existing genes, and they typically do not produce functional proteins due to accumulated mutations or alterations in their sequences.However, the original functional gene related to IBA2, from which the pseudogene is derived, has significance in biological research. IBA2 generally refers to "Ionized calcium-Binding Adapter molecule 2," which is involved in various cellular processes, particularly in the immune and nervous systems.

In its functional form, IBA2 is known to be involved in the modulation of calcium signaling within cells. Calcium ions are crucial secondary messengers in cellular signaling pathways, influencing processes such as neurotransmission, muscle contraction, and immune responses. Proteins like IBA2 that bind to calcium ions play critical roles in regulating these processes.IBA2 has been particularly studied in the context of the nervous system and immune system. In the nervous system, it is involved in neuronal development and function, influencing synaptic plasticity and neurotransmitter release. In the immune system, IBA2 may participate in the regulation of immune cell function, such as in the activation and response of macrophages and other immune cells.The study of IBA2, therefore, contributes to our understanding of calcium-dependent signaling in various physiological processes and the implications of these processes in health and disease.

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Nome do ProdutoCAS #Numero de CatalogoQuantidadePrecoUso e aplicacaoNOTAS

Calcium chloride anhydrous

10043-52-4sc-207392
sc-207392A
100 g
500 g
$65.00
$262.00
1
(1)

Aumenta a concentração de cálcio extracelular, influenciando potencialmente a sinalização de cálcio mediada pelo IBA2.

W-7

61714-27-0sc-201501
sc-201501A
sc-201501B
50 mg
100 mg
1 g
$163.00
$300.00
$1642.00
18
(1)

Inibem a calmodulina, uma proteína mensageira de ligação ao cálcio, afectando potencialmente o papel do IBA2 na sinalização do cálcio.

Phalloidin

17466-45-4sc-202763
1 mg
$229.00
33
(1)

Estabiliza os filamentos de actina, influenciando potencialmente a interação do IBA2 com o citoesqueleto.

Cytochalasin D

22144-77-0sc-201442
sc-201442A
1 mg
5 mg
$145.00
$442.00
64
(4)

Interrompe a polimerização da actina, o que pode influenciar indiretamente o papel do IBA2 na dinâmica da actina.

Jasplakinolide

102396-24-7sc-202191
sc-202191A
50 µg
100 µg
$180.00
$299.00
59
(1)

Estabiliza os filamentos de actina, podendo afetar indiretamente a função do IBA2 relacionada com a reorganização da actina.

EGTA

67-42-5sc-3593
sc-3593A
sc-3593B
sc-3593C
sc-3593D
1 g
10 g
100 g
250 g
1 kg
$20.00
$62.00
$116.00
$246.00
$799.00
23
(1)

Um quelante de cálcio, pode modular os níveis de cálcio e influenciar potencialmente a atividade do IBA2.

BAPTA, Free Acid

85233-19-8sc-201508
sc-201508A
100 mg
500 mg
$67.00
$262.00
10
(1)

Outro quelante de cálcio, utilizado para ligar especificamente iões de cálcio, afectando potencialmente o IBA2.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$94.00
$349.00
114
(2)

Inibe a Ca2+ ATPase do retículo sarcoplasmático/endoplasmático (SERCA), alterando a dinâmica do cálcio e afectando o IBA2.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$76.00
$265.00
80
(4)

Aumenta a concentração de cálcio intracelular, influenciando potencialmente a atividade do IBA2.

A23187

52665-69-7sc-3591
sc-3591B
sc-3591A
sc-3591C
1 mg
5 mg
10 mg
25 mg
$54.00
$128.00
$199.00
$311.00
23
(1)

Um ionóforo de cálcio, pode aumentar o cálcio intracelular, afectando possivelmente o IBA2.