KAD2_HUMAN Activators is a term that denotes a range of chemical compounds that can indirectly influence the function or expression of KAD2_HUMAN, a protein encoded by the AK2 gene in humans. The protein is integral to cellular energy metabolism, specifically in the reversible transfer of phosphate groups among adenine nucleotides. Consequently, the chemical compounds encompassed by the term KAD2_HUMAN Activators are primarily those that influence this energy equilibrium, thereby indirectly affecting the function and activity of KAD2_HUMAN. The first group includes ATP, ADP, and AMP, the three primary adenine nucleotides that KAD2_HUMAN interacts with directly.
As the protein's function revolves around catalyzing the exchange of phosphate groups among these nucleotides, their presence or absence can significantly influence KAD2_HUMAN's activity. Phosphocreatine, another energy-rich molecule, fits within this group as it contributes to the cellular energy equilibrium, hence indirectly influencing KAD2_HUMAN's activity. The second group includes compounds that affect the cellular energy balance more broadly. This group includes Sodium Azide, 2,4-Dinitrophenol, FCCP, Oligomycin, Sodium Fluoride, Sodium Orthovanadate, Iodoacetate, and Rotenone. These compounds interfere with various steps of cellular metabolism, from oxidative phosphorylation to glycolysis, ultimately affecting the levels of ATP, ADP, and AMP in the cell. As such, they indirectly influence KAD2_HUMAN's activity, given its role in managing the balance of these adenine nucleotides. Taken together, the compounds classified as KAD2_HUMAN Activators underline the delicate energy balance within cells, where numerous compounds and pathways converge to maintain this equilibrium.
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| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
Adenosine phosphate(Vitamin B8) | 61-19-8 | sc-278678 sc-278678A | 50 g 100 g | $160.00 $240.00 | ||
O AMP pode afetar a atividade do KAD2_HUMAN, uma vez que interage com os nucleótidos de adenina. | ||||||
Sodium azide | 26628-22-8 | sc-208393 sc-208393B sc-208393C sc-208393D sc-208393A | 25 g 250 g 1 kg 2.5 kg 100 g | $42.00 $152.00 $385.00 $845.00 $88.00 | 8 | |
A Azida de Sódio inibe a fosforilação oxidativa, afectando assim os níveis de ATP e influenciando potencialmente o KAD2_HUMAN. | ||||||
2,4-Dinitrophenol, wetted | 51-28-5 | sc-238345 | 250 mg | $58.00 | 2 | |
O 2,4-Dinitrofenol desacopla a fosforilação oxidativa, afectando os níveis de ATP e influenciando potencialmente o KAD2_HUMAN. | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
O FCCP é um protonóforo e desacoplador da fosforilação oxidativa nas mitocôndrias e pode influenciar os níveis de ATP, afectando potencialmente o KAD2_HUMAN. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
A oligomicina inibe a ATP sintase, afectando os níveis de ATP e influenciando potencialmente o KAD2_HUMAN. | ||||||
Sodium Fluoride | 7681-49-4 | sc-24988A sc-24988 sc-24988B | 5 g 100 g 500 g | $39.00 $45.00 $98.00 | 26 | |
O fluoreto de sódio inibe a enolase, uma enzima da via glicolítica, afectando os níveis de ATP e influenciando potencialmente o KAD2_HUMAN. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $45.00 $56.00 $183.00 | 142 | |
O ortovanadato de sódio inibe as tirosina fosfatases, afectando a transferência de fosfato e influenciando potencialmente o KAD2_HUMAN. | ||||||
Iodoacetic acid | 64-69-7 | sc-215183 sc-215183A | 10 g 25 g | $56.00 $97.00 | ||
O iodoacetato inibe a gliceraldeído 3-fosfato desidrogenase, afectando os níveis de ATP e influenciando potencialmente o KAD2_HUMAN. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
A rotenona inibe a cadeia de transporte de electrões mitocondrial, afectando os níveis de ATP e influenciando potencialmente o KAD2_HUMAN. | ||||||