ZNF277 Antibody (SS-17): sc-100982

ZNF277 Antibody (SS-17) is a mouse monoclonal IgG1 kappa light chain antibody that detects the ZNF277 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). anti-ZNF277 antibody (SS-17) is available as a non-conjugated format. ZNF277 protein, also known as NRIF4 or ZNF277P, is a 438 amino acid protein characterized by the presence of two C2H2-type zinc fingers, which are crucial for its function as a transcriptional repressor. ZNF277 protein is primarily localized in the nucleus, where ZNF277 plays a significant role in regulating gene expression, thereby influencing cell growth and differentiation. ZNF277′s ability to interact with other proteins, such as KAP1, highlights ZNF277′s importance in recruiting histone-modifying enzymes that can alter chromatin structure and accessibility, ultimately affecting transcriptional outcomes. ZNF277 is expressed in various human tissues, including fetal liver, lymph nodes, spleen, and peripheral blood leukocytes, underscoring ZNF277′s potential involvement in immune responses and developmental processes. ZNF277 monoclonal antibody (SS-17) versatility in applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA) makes ZNF277 monoclonal antibody (SS-17) an essential tool for researchers studying the regulatory mechanisms of gene expression and the functional roles of zinc-finger proteins in cellular processes.

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ZNF277 Antibody (SS-17) References:

1. Chromosomal mapping and genomic organization of an evolutionarily conserved zinc finger gene ZNF277.  |  Liang, H., et al. 2000. Genomics. 66: 226-8. PMID: 10860669
2. The KOX zinc finger genes: genome wide mapping of 368 ZNF PAC clones with zinc finger gene clusters predominantly in 23 chromosomal loci are confirmed by human sequences annotated in EnsEMBL.  |  Rousseau-Merck, MF., et al. 2002. Cytogenet Genome Res. 98: 147-53. PMID: 12697996
3. Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.  |  Englbrecht, CC., et al. 2004. BMC Genomics. 5: 39. PMID: 15236668
4. A novel subfamily of zinc finger genes involved in embryonic development.  |  Nakamura, M., et al. 2004. J Cell Biochem. 93: 887-95. PMID: 15449319
5. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.  |  O'Geen, H., et al. 2007. PLoS Genet. 3: e89. PMID: 17542650

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF277 Antibody (SS-17) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF277 Antibody (SS-17) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF277 Antibody (SS-17) Specifications

Alternate Product Name: ZNF277

Product Clone Name: SS-17

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-279

Epitope Target: ZNF277

Epitope Species: human

Product Reactivity/Detection: ZNF277

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZNF277 Antibody (SS-17): N/A