ZFP96 Antibody (G-6): sc-515393
- ZFP96 Antibody (G-6) is a mouse monoclonal IgG2b κ ZFP96 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 133-264 mapping within an internal region of ZFP96 of human origin
- ZFP96 Antibody (G-6) is recommended for detection of ZFP96 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZFP96 Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZFP96 Antibody (G-6) for WB applications. These reagents are now offered in bundles with ZFP96 Antibody (G-6) (see ordering information below).
ZFP96 Antibody (G-6) is a mouse monoclonal IgG2b kappa light chain antibody that detects ZFP96 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZFP96 (G-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZFP96, also known as Zinc finger protein 96 homolog or ZSCAN12, is a 604 amino acid nuclear protein characterized by its unique structure, which includes one SCAN box domain and eleven C2H2-type zinc fingers. This structural composition enables ZFP96 to bind to specific DNA sequences, thereby playing a significant role in transcriptional regulation. ZFP96 shows notable importance during pregnancy, with an eight-fold upregulation from day 13 of pregnancy to day 1 post-partum, indicating a function as a transcription factor that may switch off pro-survival genes and upregulate pro-apoptotic genes in the corpus luteum. ZFP96′s ability to modulate gene expression highlights potential impact on reproductive health and cellular apoptosis, making ZFP96 a valuable target for research in developmental biology and related fields.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZFP96 Antibody (G-6) References:
- Zinc finger peptides for the regulation of gene expression. | Klug, A. 1999. J Mol Biol. 293: 215-8. PMID: 10529348
- Three novel spermatogenesis-specific zinc finger genes. | Weissig, H., et al. 2003. FEBS Lett. 547: 61-8. PMID: 12860387
- Zinc finger proteins: getting a grip on RNA. | Brown, RS. 2005. Curr Opin Struct Biol. 15: 94-8. PMID: 15718139
- Multiple modes of RNA recognition by zinc finger proteins. | Hall, TM. 2005. Curr Opin Struct Biol. 15: 367-73. PMID: 15963892
- Cloning and characterization of a novel zinc finger protein (rZFP96) in the rat corpus luteum. | Lareu, RR., et al. 2005. Biochim Biophys Acta. 1732: 69-75. PMID: 16426687
- Epigenome-Wide DNA Methylation Profiling Identifies Differential Methylation Biomarkers in High-Grade Bladder Cancer. | Olkhov-Mitsel, E., et al. 2017. Transl Oncol. 10: 168-177. PMID: 28167242
- Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer. | Corona, RI., et al. 2020. Nat Commun. 11: 2020. PMID: 32332753
- Methylation statuses of NCOR2, PARK2, and ZSCAN12 signify densities of tumor-infiltrating lymphocytes in gastric carcinoma. | Wen, X., et al. 2022. Sci Rep. 12: 862. PMID: 35039565
- Highly Specific Droplet-Digital PCR Detection of Universally Methylated Circulating Tumor DNA in Endometrial Carcinoma. | Beinse, G., et al. 2022. Clin Chem. 68: 782-793. PMID: 35323926
- A Simple Cervicovaginal Epigenetic Test for Screening and Rapid Triage of Women With Suspected Endometrial Cancer: Validation in Several Cohort and Case/Control Sets. | Herzog, C., et al. 2022. J Clin Oncol. 40: 3828-3838. PMID: 36001862
- Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. | Bellefroid, EJ., et al. 1993. EMBO J. 12: 1363-74. PMID: 8467795
- Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. | Ishikawa, K., et al. 1997. DNA Res. 4: 307-13. PMID: 9455477
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZFP96 Antibody (G-6) | sc-515393 | 200 µg/ml | $322.00 | |||
ZFP96 Antibody (G-6): m-IgGκ BP-HRP Bundle | sc-525020 | 200 µg Ab, 40 µg BP | $361.00 | |||
ZFP96 Antibody (G-6): m-IgG2b BP-HRP Bundle | sc-549207 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZFP96 Antibody (G-6) AC | sc-515393 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZFP96 Antibody (G-6) HRP | sc-515393 HRP | 200 µg/ml | $322.00 | |||
ZFP96 Antibody (G-6) FITC | sc-515393 FITC | 200 µg/ml | $336.00 | |||
ZFP96 Antibody (G-6) PE | sc-515393 PE | 200 µg/ml | $349.00 | |||
ZFP96 Antibody (G-6) Alexa Fluor® 488 | sc-515393 AF488 | 200 µg/ml | $364.00 | |||
ZFP96 Antibody (G-6) Alexa Fluor® 546 | sc-515393 AF546 | 200 µg/ml | $364.00 | |||
ZFP96 Antibody (G-6) Alexa Fluor® 594 | sc-515393 AF594 | 200 µg/ml | $364.00 | |||
ZFP96 Antibody (G-6) Alexa Fluor® 647 | sc-515393 AF647 | 200 µg/ml | $364.00 | |||
ZFP96 Antibody (G-6) Alexa Fluor® 680 | sc-515393 AF680 | 200 µg/ml | $364.00 | |||
ZFP96 Antibody (G-6) Alexa Fluor® 790 | sc-515393 AF790 | 200 µg/ml | $364.00 |