Voriconazole N-Oxide (CAS 618109-05-0)

Voriconazole N-Oxide is a derivative of voriconazole, primarily studied for its role in the metabolism and environmental fate of voriconazole, a broad-spectrum antifungal agent. Unlike its parent compound, voriconazole N-oxide is characterized by the addition of an oxygen molecule, forming an N-oxide group. This modification significantly impacts its chemical behavior and biological activity, serving as a marker for the study of drug metabolism pathways and the elucidation of metabolic stability. In research applications, the focus on voriconazole N-oxide helps scientists understand the transformation and degradation processes of antifungal agents in biological systems, including their potential environmental impacts. By investigating the mechanism of action of voriconazole N-oxide, researchers aim to unveil the intricacies of drug metabolism, offering insights into the detoxification processes and the reactivity of drug metabolites. This, in turn, contributes to the broader field of xenobiotic metabolism, providing valuable information for the development of safer and more effective antifungal compounds with minimized environmental footprint.