Molecular structure of Vitamin B12, CAS Number: 68-19-9
Vitamin B12 (CAS 68-19-9)
See product citations (2)
Alternate Names:
Cyanocobalamin
Application:
Vitamin B12 is a coenzyme for synthesis of nucleic acids and metabolism carbohydrates
CAS Number:
68-19-9
Purity:
>95%
Molecular Weight:
1355.36
Molecular Formula:
C63H88CoN14O14P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Vitamin B12 (Cyanocobalamin) is part of a coenzyme needed for the synthesis of proteins and nucleic acids, and for the metabolism of carbohydrates. The body undergoes a conversion process to transform it into its bioactive forms, namely methylcobalamin and cobamamide. These forms act as essential cofactors for various enzymes within the body. Vitamin B12 plays a role in the synthesis of myelin. The compound is also used as an antipernicious anemia factor.
Vitamin B12 (CAS 68-19-9) References
- Heterogeneity of hepatic vitamin B12 in the rat after parenteral cyanocobalamin. | Cooksley, WG. and Tavill, AS. 1975. Clin Sci Mol Med. 49: 257-64. PMID: 1175341
- Bioavailability of vitamin B₁₂ in cows' milk. | Matte, JJ., et al. 2012. Br J Nutr. 107: 61-6. PMID: 21733330
- B vitamin therapy for homocysteine: renal function and vitamin B12 determine cardiovascular outcomes. | Spence, JD. 2013. Clin Chem Lab Med. 51: 633-7. PMID: 23449527
- Vitamin B12 deficiency - A 21st century perspective . | Shipton, MJ. and Thachil, J. 2015. Clin Med (Lond). 15: 145-50. PMID: 25824066
- Recent trends in the development of vitamin B12 derivatives for medicinal applications. | Zelder, F. 2015. Chem Commun (Camb). 51: 14004-17. PMID: 26287029
- Vitamin B₁₂ and derivatives--In vitro permeation studies across Caco-2 cell monolayers and freshly excised rat intestinal mucosa. | Netsomboon, K., et al. 2016. Int J Pharm. 497: 129-35. PMID: 26638881
- The tissue profile of metabolically active coenzyme forms of vitamin B12 differs in vitamin B12-depleted rats treated with hydroxo-B12 or cyano-B12. | Greibe, E., et al. 2018. Br J Nutr. 120: 49-56. PMID: 29936920
- Homologous G776G Variant of Transcobalamin-II Gene is Linked to Vitamin B12 Deficiency. | Al-Batayneh, KM., et al. 2020. Int J Vitam Nutr Res. 90: 151-155. PMID: 30761942
- Determination of active vitamin B12 (cobalamin) in dietary supplements and ingredients by reversed-phase liquid chromatography: Single-laboratory validation. | Qiu, X., et al. 2019. Food Chem. 298: 125010. PMID: 31284091
- Improving stability of vitamin B12 (Cyanocobalamin) using microencapsulation by spray chilling technique. | Chalella Mazzocato, M., et al. 2019. Food Res Int. 126: 108663. PMID: 31732070
- Biosynthesis of vitamin B12 by Propionibacterium freudenreichii subsp. shermanii ATCC 13673 using liquid acid protein residue of soybean as culture medium. | Assis, DA., et al. 2020. Biotechnol Prog. 36: e3011. PMID: 32356411
- Microbial and Genetic Resources for Cobalamin (Vitamin B12) Biosynthesis: From Ecosystems to Industrial Biotechnology. | Balabanova, L., et al. 2021. Int J Mol Sci. 22: PMID: 33926061
- Adaptive capacity to dietary Vitamin B12 levels is maintained by a gene-diet interaction that ensures optimal life span. | Nair, T., et al. 2022. Aging Cell. 21: e13518. PMID: 35032420
- Effect of vitamin B12 on performance and tissue selenium content in rats fed sub-toxic levels of selenite. | Chen, C., et al. 1993. Toxicology. 85: 101-15. PMID: 8303706
Inhibitor of:
CCDC162, MMAB, PCCB, SCO2, and SLC48A1.Activator of:
2310079F23Rik, 4832428D23Rik, 5-Methylcytidine, 5830415F09Rik, 8D6, ACADSB, ADAT2, AGAT, AHCYL2, ALDH1L1, ALDH6A1, Amnionless, AMT, ANKRD13D, Aprataxin, ASMTL, BC023814, BHMT, BHMT2, biotinidase, BLVRB, C7orf73, C8orf79_6430573F11Rik, CHDH, ChoKB, CHPT1, Chr-B, cSHMT, cyt19, Dbf4, DIMT1, DMGDH, Dnmt2, DPYD, E2F-5, EBP2, Erythroid lineage, Folic Acid, Formate Dehydrogenase, FTSJ3, GAMT, Gatm, GGH, GIF, GlyT1, GMPPB, GNMT, HEMK2, Hemoglobin δ, HNMT, HTF9C, HYLS1, LCMT1, LMBRD1, lysine, MAB21L1, MAT I, MAT IIα, MAT IIβ, MAT III, MBD5, MCEE, MEM Vitamins, METTL1, METTL10, METTL2, METTL25, METTL2A, METTL2B, METTL3, METTL5, MFT, MGC52110, MIBP, MMAA, MMACHC, MMADHC, MRI1, MSR, mt-Atp8, MTHFD2L, MTHFR, MTHFSD, MTR, MTRR, NANS, NNMT, NSUN1, NSUN2, NSUN5B, NSUN5C, NSUN7, NT5DC1, Olfr15, OSAP, PCMTD1, PEMT, PEPD, periaxin, PET112L, PIWIL4, POTE8, PPC Synthetase, PRMT1, PRMT10, PRMT3, PRMT6, PRMT7, RAI1, RBKS, RBM Y chromosome, RBMY1A1, RFC-1, RG9MTD2, RhCE, RNase H1, SAHH, SAHH-3, sarcosine dehydrogenase, SDS3, Selenium, SETD4, Siglec-E, SLC25A41, SLC6A15, Sm B/B′, SNURF, SPERT, Tctex3, Tomt, Transcobalamin I, Transcobalamin II, Trimethyl Histone H4, TRM12, TRMT1, TRMT112, Trmt2b, TRMT5, TRMT6, TRMT61B, TS, TYW1B, Ythdc1, YTHDF3, and ZC3H13.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vitamin B12, 100 mg | sc-296695 | 100 mg | $39.00 | |||
Vitamin B12, 1 g | sc-296695A | 1 g | $55.00 | |||
Vitamin B12, 5 g | sc-296695B | 5 g | $204.00 | |||
Vitamin B12, 25 g | sc-296695C | 25 g | $877.00 | |||
Vitamin B12, 100 g | sc-296695D | 100 g | $3414.00 | |||
Vitamin B12, 1 kg | sc-296695E | 1 kg | $9180.00 |