Molecular structure of Vindesine sulfate, CAS Number: 59917-39-4
Vindesine sulfate (CAS 59917-39-4)
Application:
Vindesine sulfate is a vinca alkaloid
CAS Number:
59917-39-4
Molecular Weight:
852.02
Molecular Formula:
C43H55N5O7•H2SO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Vindesine, a member of the vinca alkaloid family from vincristine, a natural alkaloid found in the periwinkle plant. Its mechanism of action involves the disruption of microtubules within cancer cells, thereby impeding their division and growth. Microtubules are essential cellular structures responsible for cell movement and division. Vindesine exerts its effect by binding to these microtubules and causing their disruption, effectively halting the division and growth of cancer cells.
Vindesine sulfate (CAS 59917-39-4) References
- [An improvement on determination of the related substances in vindesine sulfate and its injection]. | Chen, J. and Huang, Z. 1999. Se Pu. 17: 85-6. PMID: 12548841
- Olfactory epithelial lesions induced by various cancer chemotherapeutic agents in mice. | Kai, K., et al. 2004. Toxicol Pathol. 32: 701-9. PMID: 15580704
- Importance of administration method in high-dose anticancer chemotherapy from toxicological standpoint in rats. | Mizushima, Y., et al. 1991. Oncology. 48: 431-7. PMID: 1720885
- [A case report of Kasabach-Merritt syndrome treated with vindesine sulfate]. | Xu, YY., et al. 2019. Zhonghua Nei Ke Za Zhi. 58: 143-145. PMID: 30704202
- An uncommon perineal embryonal rhabdomyosarcoma in adult: A case report. | Qu, S., et al. 2022. Medicine (Baltimore). 101: e32529. PMID: 36596039
- Structure-activity relationships of dimeric Catharanthus alkaloids. 1. Deacetylvinblastine amide (vindesine) sulfate. | Barnett, CJ., et al. 1978. J Med Chem. 21: 88-96. PMID: 412968
- Pharmacology, clinical efficacy and adverse effects of vindesine sulfate, a new vinca alkaloid. | Cersosimo, RJ., et al. 1983. Pharmacotherapy. 3: 259-74. PMID: 6359081
- [Effect of cis-diammine dichloroplatinum, vindesine sulfate combination chemotherapy for advanced esophageal carcinoma]. | Akazawa, S., et al. 1984. Gan To Kagaku Ryoho. 11: 1018-23. PMID: 6539098
- Acute allergic reaction due to vincristine sulfate. A case report. | Gassel, WD., et al. 1984. Oncology. 41: 403-5. PMID: 6548802
- [A cooperative phase II study of vindesine sulfate in patients with solid tumors]. | . 1983. Gan To Kagaku Ryoho. 10: 2036-42. PMID: 6614938
- Phase II evaluation of vindesine sulfate in patients with advanced sarcomas. | Sordillo, PP., et al. 1981. Cancer Treat Rep. 65: 515-6. PMID: 7237472
- Basaloid squamous carcinoma of the larynx: report of a case. | Sato, M., et al. 1997. Auris Nasus Larynx. 24: 417-22. PMID: 9352836
- Effect of vindesine sulfate on the radiation-induced alterations in mouse spermatogenesis: a flow cytometric evaluation. | Jagetia, GC., et al. 1998. Mutat Res. 398: 163-74. PMID: 9626976
Inhibitor of:
Tubulin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vindesine sulfate, 1 mg | sc-205883 | 1 mg | $53.00 | |||
Vindesine sulfate, 5 mg | sc-205883A | 5 mg | $156.00 |