VCAM-1 Antibody (1.BB.619): sc-73252
- VCAM-1 Antibody (1.BB.619) is a rat monoclonal IgG1, cited in 3 publications, provided at 200 µg/ml
- raised against stromal cells from mouse bone marrow
- recommended for detection of VCAM-1 of mouse, rat and human origin by WB, IP, IF and FCM; also reactive with additional species, including porcine
- See VCAM-1 (E-10): sc-13160 for VCAM-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for VCAM-1 Antibody (1.BB.619). This work is in progress.
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VCAM-1 (1.BB.619) is a rat monoclonal IgG1 antibody. Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression appears in various human tumors including neuroblastomas, rhabdomyosarcomas, Wilms′ tumors, Ewing′s sarcomas and some primitive myeloid malignancies. Intracellular adhesion molecule-1 (ICAM-1), also known as CD54, functions as an integral membrane protein of the immunoglobulin superfamily and recognizes the B2α1 and B2αM integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also known as CD31, exists as a glycoprotein on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) emerged as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and shows deletion in 66% of patients with Kallmann′s syndrome, anosmia with secondary hypogonadism.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VCAM-1 Antibody (1.BB.619) | sc-73252 | 200 µg/ml | $322.00 |