UBCE7IP4 Antibody (F-2): sc-393432
- UBCE7IP4 Antibody (F-2) is a mouse monoclonal IgG2a κ UBCE7IP4 antibody provided at 200 µg/ml
- raised against amino acids 49-100 mapping within an internal region of UBCE7IP4 of human origin
- UBCE7IP4 Antibody (F-2) is recommended for detection of UBCE7IP4 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-UBCE7IP4 Antibody (F-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-393432 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for UBCE7IP4 Antibody (F-2) for WB applications. This reagent is now offered in a bundle with UBCE7IP4 Antibody (F-2) (see ordering information below).
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UBCE7IP4 Antibody (F-2) is a mouse monoclonal IgG2a kappa light chain antibody that detects UBCE7IP4 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). UBCE7IP4 (F-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. UBCE7IP4, also known as RNF144A, is a 292 amino acid single-pass membrane protein characterized by one RING-type zinc finger and two IBR-type zinc fingers, which are crucial for functioning as an E3 ubiquitin-protein ligase. UBCE7IP4 plays a vital role in ubiquitination, which regulates protein degradation and maintains cellular homeostasis. By facilitating ubiquitin transfer from E2 ubiquitin-conjugating enzymes, such as UBC8 and UBCH7, to target substrates, UBCE7IP4 ensures timely removal of short-lived or damaged proteins, preventing potentially harmful protein accumulation within cells. Additionally, UBCE7IP4′s RING finger domain mediates protein-DNA and protein-protein interactions, highlighting UBCE7IP4′s importance in various cellular processes, including signal transduction and gene expression regulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
UBCE7IP4 Antibody (F-2) References:
- A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4. | Martinez-Noel, G., et al. 1999. FEBS Lett. 454: 257-61. PMID: 10431818
- RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. | Lorick, KL., et al. 1999. Proc Natl Acad Sci U S A. 96: 11364-9. PMID: 10500182
- A visual intracellular classification strategy for uncharacterized human proteins. | Hoja, MR., et al. 2000. Exp Cell Res. 259: 239-46. PMID: 10942595
- Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. | Nagase, T., et al. 1996. DNA Res. 3: 17-24. PMID: 8724849
- The RING finger domain: a recent example of a sequence-structure family. | Borden, KL. and Freemont, PS. 1996. Curr Opin Struct Biol. 6: 395-401. PMID: 8804826
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UBCE7IP4 Antibody (F-2) | sc-393432 | 200 µg/ml | $316.00 | |||
UBCE7IP4 Antibody (F-2): m-IgG Fc BP-HRP Bundle | sc-526252 | 200 µg Ab; 10 µg BP | $354.00 | |||
UBCE7IP4 Antibody (F-2) X | sc-393432 X | 200 µg/0.1 ml | $316.00 | |||
UBCE7IP4 Antibody (F-2) AC | sc-393432 AC | 500 µg/ml, 25% agarose | $416.00 | |||
UBCE7IP4 Antibody (F-2) HRP | sc-393432 HRP | 200 µg/ml | $316.00 | |||
UBCE7IP4 Antibody (F-2) FITC | sc-393432 FITC | 200 µg/ml | $330.00 | |||
UBCE7IP4 Antibody (F-2) PE | sc-393432 PE | 200 µg/ml | $343.00 | |||
UBCE7IP4 Antibody (F-2) Alexa Fluor® 488 | sc-393432 AF488 | 200 µg/ml | $357.00 | |||
UBCE7IP4 Antibody (F-2) Alexa Fluor® 546 | sc-393432 AF546 | 200 µg/ml | $357.00 | |||
UBCE7IP4 Antibody (F-2) Alexa Fluor® 594 | sc-393432 AF594 | 200 µg/ml | $357.00 | |||
UBCE7IP4 Antibody (F-2) Alexa Fluor® 647 | sc-393432 AF647 | 200 µg/ml | $357.00 | |||
UBCE7IP4 Antibody (F-2) Alexa Fluor® 680 | sc-393432 AF680 | 200 µg/ml | $357.00 | |||
UBCE7IP4 Antibody (F-2) Alexa Fluor® 790 | sc-393432 AF790 | 200 µg/ml | $357.00 |