Date published: 2025-12-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

Tyramine Hydrochloride (CAS 60-19-5)

0.0(0)
Write a reviewAsk a question

See product citations (2)

Alternate Names:
4-Hydroxyphenethylamine hydrochloride; 2-(4-Hydroxyphenyl)ethylamine hydrochloride
Application:
Tyramine Hydrochloride is a naturally occurring monoamine derived from tyrosine
CAS Number:
60-19-5
Purity:
98%
Molecular Weight:
173.64
Molecular Formula:
C8H11NO•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Tyramine Hydrochloride, the hydrochloride salt of the naturally-occurring monoamine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent but cannot cross the blood-brain barrier. Tyramine hydrochloride functions as an indirect sympathomimetic agent. While it doesn′t directly trigger the activation of adrenergic receptors, it acts as a substrate for adrenergic uptake systems and monoamine oxidase. This unique role leads to the extension of adrenergic transmitter effects. Moreover, it has the capacity to stimulate the release of transmitters from adrenergic terminals. Interestingly, in certain invertebrate nervous systems, Tyramine potentially serves as a neurotransmitter.


Tyramine Hydrochloride (CAS 60-19-5) References

  1. Assay and stability-indicating micellar electrokinetic chromatography method for the simultaneous determination of valacyclovir, acyclovir and their major impurity guanine in pharmaceutical formulations.  |  Al Azzam, KM., et al. 2010. Biomed Chromatogr. 24: 535-43. PMID: 19739243
  2. Fluorogenic substrate screening for G-quadruplex DNAzyme-based sensors.  |  Cai, Y., et al. 2013. Biosens Bioelectron. 49: 312-7. PMID: 23792624
  3. Three-step biocatalytic reaction using whole cells for efficient production of tyramine from keratin acid hydrolysis wastewater.  |  Zhang, H., et al. 2016. Appl Microbiol Biotechnol. 100: 1691-1700. PMID: 26476652
  4. Tyramine Hydrochloride Based Label-Free System for Operating Various DNA Logic Gates and a DNA Caliper for Base Number Measurements.  |  Fan, D., et al. 2017. Chemphyschem. 18: 1767-1772. PMID: 28029728
  5. Enzymatically Disulfide-Crosslinked Chitosan/Hyaluronic Acid Layer-by-Layer Self-Assembled Microcapsules for Redox-Responsive Controlled Release of Protein.  |  Yang, Y., et al. 2018. ACS Appl Mater Interfaces. 10: 33493-33506. PMID: 30203959
  6. Novel shampoo reduces hair shedding by contracting the arrector pili muscle via the trace amine-associated receptor.  |  Kovacevic, M., et al. 2019. J Cosmet Dermatol. 18: 2037-2039. PMID: 31264766
  7. A self-correcting fluorescent assay of tyrosinase based on Fe-MIL-88B-NH2 nanozyme.  |  Sun, Y., et al. 2021. Mikrochim Acta. 188: 158. PMID: 33825048
  8. Anionic exopolysaccharide from Cryptococcus laurentii 70766 as an alternative for alginate for biomedical hydrogels.  |  Hamidi, M., et al. 2022. Int J Biol Macromol. 212: 370-380. PMID: 35613678
  9. Histochemistry of MAO-A and MAO-B in the locus coeruleus of the Mongolian gerbil.  |  Konradi, C., et al. 1987. J Neural Transm. 70: 369-76. PMID: 3681291
  10. Effect of centhaquine on spontaneous and evoked norepinephrine release from isolated perfused rabbit heart.  |  Bhatnagar, M., et al. 1985. Arzneimittelforschung. 35: 693-7. PMID: 3839400
  11. Radical formation in single crystals of aromatic amines and radical transformation by light.  |  Karsten, W. and Müller, A. 1981. Int J Radiat Biol Relat Stud Phys Chem Med. 39: 235-52. PMID: 6262261
  12. The tyramine challenge test as a marker for melancholia.  |  Harrison, WM., et al. 1984. Arch Gen Psychiatry. 41: 681-5. PMID: 6732426
  13. Chemical constituents of halophilic facultatively anaerobic bacteria, 1.  |  Fu, X., et al. 1995. J Nat Prod. 58: 1950-4. PMID: 8691214
  14. Age-related changes in interstitial norepinephrine. A microdialysis study in spontaneously hypertensive rats.  |  Cabassi, A., et al. 1996. Am J Hypertens. 9: 878-83. PMID: 8879344
  15. Monitoring norepinephrine levels by microdialysis in the white adipose tissue of spontaneously hypertensive rats.  |  Cabassi, A., et al. 1995. Clin Exp Pharmacol Physiol Suppl. 22: S83-5. PMID: 9072454

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tyramine Hydrochloride, 5 g

sc-208475
5 g
$63.00

Tyramine Hydrochloride, 25 g

sc-208475A
25 g
$116.00