TTC35 Antibody (A-8) is a mouse monoclonal IgG1 antibody that detects TTC35 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TTC35, also known as KIAA0103, is a 297 amino acid protein characterized by three tetratricopeptide repeats, which are crucial for mediating protein-protein interactions. These TPR motifs, consisting of a degenerate 34 amino acid sequence, play a significant role in various cellular pathways by facilitating the assembly of protein complexes. The unique structure of TTC35, with its helix-turn-helix configuration, allows stacking with other TPR repeats, enhancing ligand binding specificity. TTC35 localizes to the inner nuclear membrane, suggesting involvement in nuclear processes, and similarity to the Nicotiana tabacum GlcNAc transferase protein indicates potential function as a putative O-linked glycosyl transferase, essential for post-translational modifications that influence protein stability and function. Anti-TTC35 antibody (A-8) serves as an invaluable tool for researchers studying protein interactions and modifications.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TTC35 Antibody (A-8) | sc-166606 | 200 µg/ml | $316.00 | |||
TTC35 Antibody (A-8): m-IgG1 BP-HRP Bundle | sc-542667 | 200 µg Ab; 20 µg BP | $354.00 |