TRP2/DCT Antibody (F-9): sc-166717
- TRP2/DCT Antibody (F-9) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 60-90 near the N-terminus of TRP2 of human origin
- recommended for detection of TRP2 of mouse, rat and human origin by WB, IP, IF and ELISA
- See TRP2/DCT (C-9): sc-74439 for TRP2/DCT antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TRP2/DCT Antibody (F-9) for WB applications. These reagents are now offered in bundles with TRP2/DCT Antibody (F-9) (see ordering information below).
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TRP2 Antibody (F-9) is a mouse monoclonal IgG1 antibody that detects TRP2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TRP2, also known as tyrosinase-related protein 2, plays a crucial role in the melanin biosynthesis pathway, specifically in the conversion of DOPA to dopachrome, which is a key step in the production of eumelanin and pheomelanin. TRP2 is primarily located in the melanosomes of melanocytes, where TRP2 works with other enzymes, including tyrosinase and TRP1, to facilitate melanin synthesis. Proper functioning of TRP2 is vital for normal pigmentation; defects in TRP2 activity can lead to pigmentation disorders such as oculocutaneous albinism. Additionally, TRP2 interacts with TRP1 and tyrosinase, forming a multi-enzyme complex that enhances stability and activity of these proteins, thereby ensuring efficient melanin production. Anti-TRP2 antibody (F-9) is an essential tool for researchers studying pigmentation, melanin biosynthesis, and related genetic disorders, providing reliable detection and characterization of TRP2 in various experimental settings.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRP2/DCT Antibody (F-9) | sc-166717 | 200 µg/ml | $316.00 | |||
TRP2/DCT Antibody (F-9): m-IgG Fc BP-HRP Bundle | sc-540145 | 200 µg Ab; 10 µg BP | $354.00 | |||
TRP2/DCT Antibody (F-9): m-IgG1 BP-HRP Bundle | sc-541932 | 200 µg Ab; 20 µg BP | $354.00 | |||
TRP2/DCT (F-9) Neutralizing Peptide | sc-166717 P | 100 µg/0.5 ml | $68.00 |