Molecular structure of Triphenyl Compound A, CAS Number: 21306-65-0
Triphenyl Compound A (CAS 21306-65-0)
See product citations (1)
Alternate Names:
TPH A
Application:
Triphenyl Compound A is a pirin inhibitor
CAS Number:
21306-65-0
Purity:
≥98%
Molecular Weight:
399.5
Molecular Formula:
C21H21NO3S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Triphenyl Compound A is an inhibitor of the nuclear protein pirin. TPh A (Triphenyl compound A) inhibits the interaction between Bcl3 oncoprotein and the nuclear protein pirin. TPh A inihibits melanoma cell migration.
Triphenyl Compound A (CAS 21306-65-0) References
- A small-molecule inhibitor shows that pirin regulates migration of melanoma cells. | Miyazaki, I., et al. 2010. Nat Chem Biol. 6: 667-73. PMID: 20711196
- Unbiased binding assays for discovering small-molecule probes and drugs. | Kemp, MM., et al. 2012. Bioorg Med Chem. 20: 1979-89. PMID: 22230199
- A novel small compound accelerates dermal wound healing by modifying infiltration, proliferation and migration of distinct cellular components in mice. | Yamaoka, H., et al. 2014. J Dermatol Sci. 74: 204-13. PMID: 24702853
- Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. | Komai, K., et al. 2015. FEBS Lett. 589: 738-43. PMID: 25680527
- Role of Pirin, an Oxidative Stress Sensor Protein, in Epithelial Carcinogenesis. | Perez-Dominguez, F., et al. 2021. Biology (Basel). 10: PMID: 33557375
Inhibitor of:
pirin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Triphenyl Compound A, 1 mg | sc-364144 | 1 mg | $47.00 | |||
Triphenyl Compound A, 5 mg | sc-364144A | 5 mg | $101.00 |