TRIM16 Antibody (B-6): sc-398851
- TRIM16 Antibody (B-6) is a mouse monoclonal IgG1 κ TRIM16 antibody, cited in 5 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 181-206 within an internal region of TRIM16 of human origin
- TRIM16 Antibody (B-6) is recommended for detection of TRIM16 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TRIM16 Antibody (B-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TRIM16 (B-6): sc-398851.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for TRIM16 Antibody (B-6) for WB applications. This reagent is now offered in a bundle with TRIM16 Antibody (B-6) (see ordering information below).
TRIM16 Antibody (B-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects TRIM16 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-TRIM16 antibody (B-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TRIM16, also known as estrogen-responsive B box protein (EBBP), is a 564 amino acid member of the tripartite motif (TRIM) family, characterized by a conserved TRIM domain that includes a coiled-coil region, two B box-type zinc fingers, and one B30.2/SPRY domain. TRIM16 is predominantly expressed in the testis, ovary, small intestine, colon, placenta, heart, skeletal muscle, and mammary gland, with notably higher expression levels in fetal tissues compared to adult counterparts. TRIM16 plays a crucial role in regulating keratinocyte differentiation, particularly in basal keratinocytes, and has been implicated in the modulation of histone acetylation in retinoid-resistant cancer cells, suggesting potential as a therapeutic target. TRIM16′s ability to interact with specific proteins involved in cellular signaling pathways further underscores importance in various biological processes, making TRIM16 monoclonal antibody (B-6) an essential tool for researchers studying diverse functions and implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TRIM16 Antibody (B-6) References:
- The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation. | Beer, HD., et al. 2002. J Biol Chem. 277: 20740-9. PMID: 11919186
- The estrogen-responsive B box protein: a novel enhancer of interleukin-1beta secretion. | Munding, C., et al. 2006. Cell Death Differ. 13: 1938-49. PMID: 16575408
- The estrogen-responsive B box protein is a novel regulator of the retinoid signal. | Cheung, BB., et al. 2006. J Biol Chem. 281: 18246-56. PMID: 16636064
- TRIM family proteins and their emerging roles in innate immunity. | Ozato, K., et al. 2008. Nat Rev Immunol. 8: 849-60. PMID: 18836477
- The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation. | Raif, A., et al. 2009. Cancer Lett. 277: 82-90. PMID: 19147277
- The novel estrogen-responsive B-box protein (EBBP) gene is tamoxifen-regulated in cells expressing an estrogen receptor DNA-binding domain mutant. | Liu, HL., et al. 1998. Mol Endocrinol. 12: 1733-48. PMID: 9817599
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRIM16 Antibody (B-6) | sc-398851 | 200 µg/ml | $316.00 | |||
TRIM16 Antibody (B-6): m-IgG Fc BP-HRP Bundle | sc-526329 | 200 µg Ab; 10 µg BP | $354.00 | |||
TRIM16 Antibody (B-6) AC | sc-398851 AC | 500 µg/ml, 25% agarose | $416.00 | |||
TRIM16 Antibody (B-6) HRP | sc-398851 HRP | 200 µg/ml | $316.00 | |||
TRIM16 Antibody (B-6) FITC | sc-398851 FITC | 200 µg/ml | $330.00 | |||
TRIM16 Antibody (B-6) PE | sc-398851 PE | 200 µg/ml | $343.00 | |||
TRIM16 Antibody (B-6) Alexa Fluor® 488 | sc-398851 AF488 | 200 µg/ml | $357.00 | |||
TRIM16 Antibody (B-6) Alexa Fluor® 546 | sc-398851 AF546 | 200 µg/ml | $357.00 | |||
TRIM16 Antibody (B-6) Alexa Fluor® 594 | sc-398851 AF594 | 200 µg/ml | $357.00 | |||
TRIM16 Antibody (B-6) Alexa Fluor® 647 | sc-398851 AF647 | 200 µg/ml | $357.00 | |||
TRIM16 Antibody (B-6) Alexa Fluor® 680 | sc-398851 AF680 | 200 µg/ml | $357.00 | |||
TRIM16 Antibody (B-6) Alexa Fluor® 790 | sc-398851 AF790 | 200 µg/ml | $357.00 | |||
TRIM16 (B-6) Neutralizing Peptide | sc-398851 P | 100 µg/0.5 ml | $68.00 |