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trans-1-Decalone (CAS 21370-71-8)

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Alternate Names:
trans-Decahydro-1-naphthalenone
CAS Number:
21370-71-8
Molecular Weight:
152.23
Molecular Formula:
C10H16O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Trans-1-Decalone (trans-1-D) is a synthetic cyclopentanone derivative that holds significant potential in laboratory experiments and scientific research. As a member of the ketone class of compounds, it offers a wide range of applications in various scientific investigations. Notably, trans-1-Decalone has been explored for its potential as an anti-inflammatory agent by inhibiting the production of pro-inflammatory cytokines. Its effectiveness as an anti-tumor agent has also been investigated due to its ability to impede cancer cell proliferation. Furthermore, trans-1-Decalone has shown promise as a potential treatment for neurological disorders by reducing dopamine levels in the brain. The mechanisms of action associated with trans-1-Decalone are diverse. It is believed to function as an inhibitor of the enzyme cyclooxygenase-2 (COX-2), responsible for producing pro-inflammatory cytokines. Additionally, trans-1-Decalone has demonstrated the ability to inhibit the activity of the enzyme 5-lipoxygenase (5-LOX), which contributes to the production of leukotrienes involved in the inflammatory response. Furthermore, it modulates the activity of acetylcholinesterase, an enzyme responsible for acetylcholine breakdown, thus affecting neurotransmitter levels. In summary, trans-1-Decalone showcases its potential as a versatile compound in scientific research, with applications ranging from anti-inflammatory and anti-tumor properties to its influence on neurological disorders through various mechanisms of action.


trans-1-Decalone (CAS 21370-71-8) References

  1. Optical Rotatory Dispersion Studies. XLI.1 α-Haloketones (Part 9).2 Bromination of Optically Active cis-1-Decalone. Demonstration of Conformational Mobility by Rotatory Dispersion3  |  Carl Djerassi and J. Staunton. 1961,. J. Am. Chem. Soc. 83, 3,: 736–743.
  2. Mechanistic study of the photosensitized oxidation of cis-decalin and trans-decalin  |  https://www.sciencedirect.com/science/article/abs/pii/101060309087114Q. 15 July 1990,. Journal of Photochemistry and Photobiology A: Chemistry. Volume 53, Issue 1,: Pages 69-75.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

trans-1-Decalone, 1 g

sc-237137
1 g
$172.00