Date published: 2026-4-29

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Tildipirosin (CAS 328898-40-4)

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Alternate Names:
20,23-dipiperidinyl-mycaminosyl-tylonolide
Application:
Tildipirosin is an antibiotic
CAS Number:
328898-40-4
Molecular Weight:
734.01
Molecular Formula:
C41H71N3O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tildiprosin is an antibiotic derived from a tylosin derivative by iodination and reaction with piperidine. The introduction of a third basic moiety into the tylosin core provides a wider spectrum of antibiotic action than the dibasic analogues such as tilmicosin, in particular good protection against Pasteurella in livestock. Tildipirosin′s interaction with the ribosomal site of action differs from that of tylosin and tilmicosin.


Tildipirosin (CAS 328898-40-4) References

  1. Pharmacokinetics of tildipirosin in pig tonsils.  |  Torres, F., et al. 2016. J Vet Pharmacol Ther. 39: 199-201. PMID: 26935349
  2. Comparative transcriptional profiling of tildipirosin-resistant and sensitive Haemophilus parasuis.  |  Lei, Z., et al. 2017. Sci Rep. 7: 7517. PMID: 28790420
  3. Pharmacokinetics of tildipirosin in beagle dogs.  |  Wang, J., et al. 2018. J Vet Pharmacol Ther. 41: e49-e52. PMID: 28892155
  4. Pharmacokinetics and Pharmacodynamics of Tildipirosin Against Pasteurella multocida in a Murine Lung Infection Model.  |  Zeng, D., et al. 2018. Front Microbiol. 9: 1038. PMID: 29867911
  5. Optimal Regimens and Cutoff Evaluation of Tildipirosin Against Pasteurella multocida.  |  Lei, Z., et al. 2018. Front Pharmacol. 9: 765. PMID: 30093860
  6. Pharmacokinetics and bioavailability of tildipirosin in rabbits following single-dose intravenous and intramuscular administration.  |  Xiong, J., et al. 2020. J Vet Pharmacol Ther. 43: 448-453. PMID: 32542744
  7. Pharmacokinetics of Tildipirosin in Ewes after Intravenous, Intramuscular and Subcutaneous Administration.  |  Galecio, JS., et al. 2020. Animals (Basel). 10: PMID: 32752202
  8. Tildipirosin: An effective antibiotic against Glaesserella parasuis from an in vitro analysis.  |  Peres, PR., et al. 2020. Vet Anim Sci. 10: 100136. PMID: 32964167
  9. Pharmacokinetics and bioavailability of tildipirosin following intravenous and subcutaneous administration in horses.  |  Abu-Basha, EA., et al. 2021. J Vet Pharmacol Ther. 44: 544-551. PMID: 33609061
  10. Effect of metaphylactic administration of tildipirosin on the incidence of pneumonia and otitis and on the upper respiratory tract and fecal microbiome of preweaning Holstein calves.  |  Bringhenti, L., et al. 2021. J Dairy Sci. 104: 6020-6038. PMID: 33685693
  11. Pharmacokinetics of Tildipirosin in Plasma, Milk, and Somatic Cells Following Intravenous, Intramuscular, and Subcutaneous Administration in Dairy Goats.  |  Galecio, JS., et al. 2022. Pharmaceutics. 14: PMID: 35456694
  12. Pharmacokinetics of tildipirosin in horses after intravenous and intramuscular administration and its potential muscle damage.  |  Galecio, JS., et al. 2022. Res Vet Sci. 152: 20-25. PMID: 35908422

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tildipirosin, 1 mg

sc-397306
1 mg
$322.00

Tildipirosin, 5 mg

sc-397306A
5 mg
$1193.00

Good afternoon! Tell me, please, can I use this as an analytical standard? Can you specify the cost of this products and delivery?

Asked by: monid
Thank you for your message. Our Customer Service department will contact you asap with the lead time and price quotation for this product. Most of our products are currently on stock in our European Support Office and we ship these over night, however specific delivery time can depend by destination, amount and current availability.
Answered by: Technical Support Europe
Date published: 2017-09-21
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Rated 5 out of 5 by from Andersen NM; et alAndersen NM; et al. (PubMed ID: 22926570) determined that Tildipirosin uses methylation at key rRNA nucleotides to induce cytoxicity in Mannheimia haemolytica and Pasteurella multocida, in cattle and swine. -SCBT Publication Review
Date published: 2015-05-10
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Tildipirosin is rated 5.0 out of 5 by 1.
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