Date published: 2025-10-19

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Thyroxine 4′-O-Sulfate (CAS 77074-49-8)

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Alternate Names:
Thyroxine Hydrogen Sulfate; O-[3,5-Diiodo-4-(sulfooxy)phenyl]-3,5-diiodo-L-tyrosine
CAS Number:
77074-49-8
Molecular Weight:
856.93
Molecular Formula:
C15H11I4NO7S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Thyroxine 4′-O-Sulfate, referred to as T4 sulfate or T4S, falls within the category of organic compounds known as phenylalanine and derivatives. These compounds encompass phenylalanine or its derivatives that arise from reactions at the amino or carboxy group, or substitutions of glycine hydrogen with a heteroatom. Thyroxine 4′-O-Sulfate, in particular, is characterized as a molecule with limited solubility in water and a relatively neutral nature.


Thyroxine 4′-O-Sulfate (CAS 77074-49-8) References

  1. Structural Insights into Endobiotic Reactivation by Human Gut Microbiome-Encoded Sulfatases.  |  Ervin, SM., et al. 2020. Biochemistry. 59: 3939-3950. PMID: 32993284
  2. Development of a microphysiological skin-liver-thyroid Chip3 model and its application to evaluate the effects on thyroid hormones of topically applied cosmetic ingredients under consumer-relevant conditions.  |  Tao, TP., et al. 2023. Front Pharmacol. 14: 1076254. PMID: 36843954

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Thyroxine 4′-O-Sulfate, 1 mg

sc-474751
1 mg
$311.00