Date published: 2026-4-24

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Thymine-1-acetic acid (CAS 20924-05-4)

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Application:
Thymine-1-acetic acid is Thymine-1-acetic acid is a useful reagent in Oligonucleotide synthesis.
CAS Number:
20924-05-4
Purity:
≥97%
Molecular Weight:
184.15
Molecular Formula:
C7H8N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Thymine-1-acetic acid is used in biochemical studies involving nucleic acid derivatives and their interactions with various biological systems. Thymine-1-acetic acid is instrumental in exploring the modification of nucleotide structures and understanding their role in DNA and RNA stability. Thymine-1-acetic acid serves as a key reagent in synthesizing labeled DNA probes used in molecular biology for gene expression analysis and other genetic investigations. This includes its use in studying the mechanisms of nucleotide recognition and binding by proteins, which is necessary for elucidating cellular processes like transcription and replication. Thymine-1-acetic acid is utilized in the development of novel bioconjugates for targeted chemical delivery systems, focusing on its integration into biologically active molecules.


Thymine-1-acetic acid (CAS 20924-05-4) References

  1. An efficient, convenient solid-phase synthesis of amino acid-modified peptide nucleic acid monomers and oligomers.  |  Balaji, BS., et al. 2006. Bioconjug Chem. 17: 551-8. PMID: 16536490
  2. A light-responsive reversible molecule-gated system using thymine-modified mesoporous silica nanoparticles.  |  He, D., et al. 2012. Langmuir. 28: 4003-8. PMID: 22309360
  3. Semiconductive and magnetic one-dimensional coordination polymers of Cu(II) with modified nucleobases.  |  Amo-Ochoa, P., et al. 2013. Inorg Chem. 52: 11428-37. PMID: 24040754
  4. Functionalized gold nanoparticles/reduced graphene oxide nanocomposites for ultrasensitive electrochemical sensing of mercury ions based on thymine-mercury-thymine structure.  |  Wang, N., et al. 2016. Biosens Bioelectron. 79: 320-6. PMID: 26720921
  5. Novel thymine-functionalized MIL-101 prepared by post-synthesis and enhanced removal of Hg(2+) from water.  |  Luo, X., et al. 2016. J Hazard Mater. 306: 313-322. PMID: 26774986
  6. Copper(II)-Thymine Coordination Polymer Nanoribbons as Potential Oligonucleotide Nanocarriers.  |  Vegas, VG., et al. 2017. Angew Chem Int Ed Engl. 56: 987-991. PMID: 27936318
  7. Microwave-assisted synthesis of thymine-functionalized graphitic carbon nitride quantum dots as a fluorescent nanoprobe for mercury(II).  |  Achadu, OJ. and Revaprasadu, N. 2018. Mikrochim Acta. 185: 461. PMID: 30219975
  8. Multifunctional coordination polymers based on copper with modified nucleobases, easily modulated in size and conductivity.  |  Vegas, VG., et al. 2019. J Inorg Biochem. 200: 110805. PMID: 31470343
  9. A portable selective electrochemical sensor amplified with Fe3O4@Au-cysteamine-thymine acetic acid as conductive mediator for determination of mercuric ion.  |  Butmee, P., et al. 2021. Talanta. 221: 121669. PMID: 33076175
  10. Thymine-Functionalized Gold Nanoparticles (Au NPs) for a Highly Sensitive Fiber-Optic Surface Plasmon Resonance Mercury Ion Nanosensor.  |  Yuan, H., et al. 2021. Nanomaterials (Basel). 11: PMID: 33557300
  11. Lactobionic acid-modified thymine-chitosan nanoparticles as potential carriers for methotrexate delivery.  |  Wang, J., et al. 2021. Carbohydr Res. 501: 108275. PMID: 33657498
  12. Chain-End Effects on Supramolecular Poly(ethylene glycol) Polymers.  |  Brás, A., et al. 2021. Polymers (Basel). 13: PMID: 34300992
  13. Molecular recognition and removal properties of Langmuir–Blodgett films of nucleolipid amphiphiles bearing thymine headgroup  |  Takeshi Kondo, Kazuyoshi Ota, Yosuke Matsushita, Ryoji Kimura, Takeshi Kawai. 2006. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 273: 101-108.
  14. Ionic liquid mediated synthesis of labelled peptide nucleic acid monomer  |  CK Athira, Priyadharshini Manikandan, Elango Kandasamy, Prasanna Ramani. 2019. 18: 1735-1739.
  15. Removal of some commercial pesticides from aqueous dispersions using as flocculant a thymine-containing chitosan derivative  |  Luminita Ghimici, Ionel Adrian Dinu. 2019. Separation and Purification Technology. 209: 698-706.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Thymine-1-acetic acid, 5 g

sc-255660
5 g
$185.00