Date published: 2025-11-30

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tetranor-PGFM (CAS 23109-94-6)

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Alternate Names:
tetranor-Prostaglandin F Metabolite
Application:
tetranor-PGFM is a useful biomarker
CAS Number:
23109-94-6
Molecular Weight:
330.37
Molecular Formula:
C16H26O7
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The major urinary metabolite of PGF2α.1,2,3,4 Normal healthy females excrete 7-13 µg of tetranor-PGFM per day compared to 11-59 µg per day for healthy males.2 In pregnant females, tetranor-PGFM levels in the urine are 2 to 5-fold higher and diminish to pre-pregnancy levels soon after labor.2


tetranor-PGFM (CAS 23109-94-6) References

  1. PGFM (13,14-dihydro-15-keto-PGF(2alpha)) in pregnant and pseudo-pregnant Iberian lynx: a new noninvasive pregnancy marker for felid species.  |  Finkenwirth, C., et al. 2010. Theriogenology. 73: 530-40. PMID: 20022361
  2. Comparative metabolism of PGFM (13,14-dihydro-15-keto-PGF2α) in feces of felids.  |  Dehnhard, M., et al. 2014. Theriogenology. 81: 733-43. PMID: 24433781
  3. Metabolism of prostaglandin F2alpha in Eurasian lynx (Lynx lynx) and Asian leopard cat (Prionailurus bengalensis euptilura).  |  Dehnhard, M., et al. 2017. Reprod Domest Anim. 52 Suppl 2: 45-51. PMID: 28111808
  4. Prostaglandin D2 metabolite in urine is an index of food allergy.  |  Maeda, S., et al. 2017. Sci Rep. 7: 17687. PMID: 29247205
  5. Mass spectrometry and multivariate analysis to classify cervical intraepithelial neoplasia from blood plasma: an untargeted lipidomic study.  |  Neves, ACO., et al. 2018. Sci Rep. 8: 3954. PMID: 29500376
  6. Development of Monoclonal Antibody-Based EIA for Tetranor-PGDM which Reflects PGD2 Production in the Body.  |  Nagata, N., et al. 2021. J Immunol Res. 2021: 5591115. PMID: 33997056
  7. Quantitative studies on prostaglandin synthesis in man. II. Determination of the major urinary metabolite of prostaglandins F1 alpha and F2 alpha.  |  Hamberg, M. 1973. Anal Biochem. 55: 368-78. PMID: 4750680
  8. Quantitative studies on prostaglandin synthesis in man. 3. Excretion of the major urinary metabolite of prostaglandins F 1 alpha and F 2 alpha during pregnancy.  |  Hamberg, M. 1974. Life Sci. 14: 247-52. PMID: 4813589
  9. On the metabolism of prostaglandin F-2-alpha in female subjects.  |  Granström, E. and Samuelsson, B. 1971. J Biol Chem. 246: 5254-63. PMID: 5125749
  10. The structure of a urinary metabolite of prostaglandin F2a in man.  |  Granström, E. and Samuelsson, B. 1969. J Am Chem Soc. 91: 3398-400. PMID: 5791928

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

tetranor-PGFM, 25 µg

sc-205523
25 µg
$130.00

tetranor-PGFM, 50 µg

sc-205523A
50 µg
$248.00