Stomatin Antibody (E-5): sc-376869
- Stomatin Antibody (E-5) is a mouse monoclonal IgG2b κ Stomatin antibody, cited in 9 publications, provided at 200 µg/ml
- raised against amino acids 1-45 mapping at the N-terminus of Stomatin of human origin
- Stomatin Antibody (E-5) is recommended for detection of Stomatin of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Stomatin Antibody (E-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP is the preferred secondary detection reagent for Stomatin Antibody (E-5) for WB and IHC(P) applications. This reagent is now offered in a bundle with Stomatin Antibody (E-5) (see ordering information below).
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Stomatin Antibody (E-5) is a mouse monoclonal IgG2b kappa light chain antibody that detects Stomatin protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Stomatin antibody (E-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Stomatin is an integral membrane protein predominantly located in lipid/protein-rich microdomains across nearly all human tissues, playing a crucial role in maintaining cellular integrity and function. Stomatin′s presence in these microdomains is vital for proper signal transduction and cell communication, as Stomatin may regulate the movement of cations through ion channels and transporters. Absence of Stomatin can lead to dysregulation of sodium and potassium ion concentrations within erythrocytes, potentially resulting in cellular dysfunction. Stomatin serves as a cytoskeletal anchor, contributing to the structural stability of cells. Stomatin features a single hydrophobic domain near its N-terminus and includes a phosphorylation site, which may be important for regulatory functions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Stomatin Antibody (E-5) References:
- Association of stomatin with lipid-protein complexes in the plasma membrane and the endocytic compartment. | Snyers, L., et al. 1999. Eur J Cell Biol. 78: 802-12. PMID: 10604657
- Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts. | Salzer, U. and Prohaska, R. 2001. Blood. 97: 1141-3. PMID: 11159550
- Stomatin is a major lipid-raft component of platelet alpha granules. | Mairhofer, M., et al. 2002. Blood. 100: 897-904. PMID: 12130500
- Association of stomatin with lipid bodies. | Umlauf, E., et al. 2004. J Biol Chem. 279: 23699-709. PMID: 15024010
- Stomatin modulates gating of acid-sensing ion channels. | Price, MP., et al. 2004. J Biol Chem. 279: 53886-91. PMID: 15471860
- Differentially expressed transcripts from phenotypically identified olfactory sensory neurons. | Yu, TT., et al. 2005. J Comp Neurol. 483: 251-62. PMID: 15682396
- Characterization of the stomatin domain involved in homo-oligomerization and lipid raft association. | Umlauf, E., et al. 2006. J Biol Chem. 281: 23349-56. PMID: 16766530
- Lipid raft-associated stomatin enhances cell fusion. | Lee, JH., et al. 2017. FASEB J. 31: 47-59. PMID: 27663861
- Stomatin is highly expressed in exosomes of different origin and is a promising candidate as an exosomal marker. | Skryabin, GO., et al. 2021. J Cell Biochem. 122: 100-115. PMID: 32951259
- Stomatin-Mediated Inhibition of the Akt Signaling Axis Suppresses Tumor Growth. | Rahman, NIA., et al. 2021. Cancer Res. 81: 2318-2331. PMID: 33757977
- Stomatin-Like Protein-2: A Potential Target to Treat Mitochondrial Cardiomyopathy. | Hu, Y., et al. 2021. Heart Lung Circ. 30: 1449-1455. PMID: 34088631
- Stomatin. | Stewart, GW. 1997. Int J Biochem Cell Biol. 29: 271-4. PMID: 9147127
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Stomatin Antibody (E-5) | sc-376869 | 200 µg/ml | $322.00 | |||
Stomatin Antibody (E-5): m-IgG2b BP-HRP Bundle | sc-548758 | 200 µg Ab; 10 µg BP | $361.00 | |||
Stomatin Antibody (E-5) AC | sc-376869 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Stomatin Antibody (E-5) HRP | sc-376869 HRP | 200 µg/ml | $322.00 | |||
Stomatin Antibody (E-5) FITC | sc-376869 FITC | 200 µg/ml | $336.00 | |||
Stomatin Antibody (E-5) PE | sc-376869 PE | 200 µg/ml | $349.00 | |||
Stomatin Antibody (E-5) Alexa Fluor® 488 | sc-376869 AF488 | 200 µg/ml | $364.00 | |||
Stomatin Antibody (E-5) Alexa Fluor® 546 | sc-376869 AF546 | 200 µg/ml | $364.00 | |||
Stomatin Antibody (E-5) Alexa Fluor® 594 | sc-376869 AF594 | 200 µg/ml | $364.00 | |||
Stomatin Antibody (E-5) Alexa Fluor® 647 | sc-376869 AF647 | 200 µg/ml | $364.00 | |||
Stomatin Antibody (E-5) Alexa Fluor® 680 | sc-376869 AF680 | 200 µg/ml | $364.00 | |||
Stomatin Antibody (E-5) Alexa Fluor® 790 | sc-376869 AF790 | 200 µg/ml | $364.00 |