SPATA25 Antibody (H-3): sc-374631

SPATA25 Antibody (H-3) is a mouse monoclonal IgG3 antibody that detects SPATA25 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-SPATA25 antibody (H-3) is available as the non-conjugated form. SPATA25, also known as spermatogenesis-associated protein 25 or TSG23 (testis-specific gene 23 protein), is a 227 amino acid single-pass membrane protein that plays a crucial role in spermatogenesis, a process essential for male fertility. SPATA25 is predominantly expressed in the testis, where levels are approximately 60-fold higher in adult testis compared to fetal testis, highlighting significance during the later stages of male reproductive development. The gene encoding SPATA25 is located on human chromosome 20q13.12, a region that encompasses nearly 63 million bases and contains over 600 genes, some of which are implicated in various neurological and genetic disorders. Notably, chromosome 20 also harbors genes that are believed to be important for seminal production, making SPATA25 a potential target for research into male contraception strategies. Anti-SPATA25 antibody (H-3)′s ability to effectively detect SPATA25 across multiple applications makes this product an invaluable tool for researchers studying male reproductive biology and related fields.

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SPATA25 Antibody (H-3) References:

1. Early pattern of epilepsy in the ring chromosome 20 syndrome.  |  Ville, D., et al. 2006. Epilepsia. 47: 543-9. PMID: 16529619
2. Trisomy 20 mosaicism and nonmosaic trisomy 20: a report of 2 cases.  |  Joó, JG., et al. 2006. J Reprod Med. 51: 209-12. PMID: 16674019
3. The imaging appearance of Creutzfeldt-Jakob disease caused by the E200K mutation.  |  Fulbright, RK., et al. 2006. Magn Reson Imaging. 24: 1121-9. PMID: 17071334
4. Eppin: an epididymal protease inhibitor and a target for male contraception.  |  O'Rand, MG., et al. 2007. Soc Reprod Fertil Suppl. 63: 445-53. PMID: 17566290
5. A locus on chromosome 20 encompassing genes that are highly expressed in the epididymis.  |  Lundwall, A. 2007. Asian J Androl. 9: 540-4. PMID: 17589793
6. Alagille syndrome with deletion 20p12.2-p12.3 and hypoplastic left heart.  |  Robert, ML., et al. 2007. Clin Dysmorphol. 16: 241-6. PMID: 17786115
7. Ring chromosome 20 syndrome without deletions of the subtelomeric and CHRNA4--KCNQ2 genes loci.  |  Elghezal, H., et al. 2007. Eur J Med Genet. 50: 441-5. PMID: 17851150
8. Developmental expression pattern of a novel gene, TSG23/Tsg23, suggests a role in spermatogenesis.  |  Zhou, Y., et al. 2009. Mol Hum Reprod. 15: 223-30. PMID: 19240080

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-SPATA25 Antibody (H-3) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-SPATA25 Antibody (H-3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

SPATA25 Antibody (H-3) Specifications

Alternate Product Name: SPATA25

Product Clone Name: H-3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃

Amino Acids: 9-45

Epitope Target: SPATA25

Epitope Species: human

Product Reactivity/Detection: SPATA25

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₃ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for SPATA25 Antibody (H-3): P: Blocking Peptide