Serotonin Antibody (YC5/45): sc-58031

Serotonin Antibody (YC5/45) is a rat monoclonal IgG2c antibody that detects Serotonin protein of broad mammalian origin by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Serotonin antibody (YC5/45) is available as a non-conjugated format. Serotonin, also known as 5-hydroxytryptamine (5-HT), is a crucial monoamine neurotransmitter synthesized in serotonergic neurons within the central nervous system (CNS) and in enterochromaffin cells of the gastrointestinal tract. The primary source of serotonin in the CNS is the neurons of the Raphe nuclei, and signaling is primarily regulated through reuptake mechanisms that remove serotonin from the synaptic cleft. This neurotransmitter plays a vital role in various physiological processes, including mood regulation, sleep cycles, appetite control, and the modulation of pain and anxiety responses. Serotonin′s structure allows interaction with a variety of receptors, including 5-HT receptors, which are involved in numerous signaling pathways affecting both central and peripheral nervous system functions. Dysregulation of serotonin levels is linked to several psychiatric and neurological disorders, such as depression, anxiety, and bipolar disorder, making serotonin a significant target for therapeutic interventions. Agents that inhibit serotonin reuptake, including selective serotonin reuptake inhibitors (SSRIs) and certain recreational drugs, highlight serotonin′s importance in both health and disease.

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Serotonin Antibody (YC5/45) References:

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