SEC14L3 Antibody (E-1): sc-515334
- SEC14L3 Antibody (E-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 201-243 mapping within an internal region of SEC14L3 of human origin
- Anti-SEC14L3 Antibody (E-1) is recommended for detection of SEC14L3 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-SEC14L3 Antibody (E-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for SEC14L3 Antibody (E-1) for WB applications. These reagents are now offered in bundles with SEC14L3 Antibody (E-1) (see ordering information below).
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SEC14L3 Antibody (E-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects SEC14L3 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-SEC14L3 antibody (E-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. SEC14L3 plays a crucial role in lipid metabolism and is involved in the transport of lipids within cells, which is essential for maintaining cellular homeostasis and signaling pathways. Disruptions in lipid transport can lead to various diseases, including metabolic disorders and neurodegenerative conditions, highlighting the importance of SEC14L3 in health and disease. SEC14L3 is primarily located in the cytoplasm and is associated with cellular membranes, where SEC14L3 facilitates the transfer of lipids to specific cellular compartments, thereby influencing membrane composition and function. Understanding the dynamics of SEC14L3 and its interactions with other proteins can provide insights into the mechanisms underlying lipid-related pathologies and potential therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SEC14L3 Antibody (E-1) References:
- Chromosome 22 workshop report. | Schwab, SG. and Wildenauer, DB. 1999. Am J Med Genet. 88: 276-8. PMID: 10374745
- Disease genes and chromosomes: disease maps of the human genome. Chromosome 22. | Gilbert, F. 1998. Genet Test. 2: 89-97. PMID: 10464604
- Constitutional rearrangements of chromosome 22 as a cause of neurofibromatosis 2. | Tsilchorozidou, T., et al. 2004. J Med Genet. 41: 529-34. PMID: 15235024
- Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome. | Paylor, R., et al. 2006. Proc Natl Acad Sci U S A. 103: 7729-34. PMID: 16684884
- Analyses of the associations between the genes of 22q11 deletion syndrome and schizophrenia. | Arinami, T. 2006. J Hum Genet. 51: 1037-1045. PMID: 16969581
- Mutational spectrum of the NF2 gene: a meta-analysis of 12 years of research and diagnostic laboratory findings. | Ahronowitz, I., et al. 2007. Hum Mutat. 28: 1-12. PMID: 16983642
- BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility. | Zheng, X., et al. 2006. BMC Cancer. 6: 262. PMID: 17090304
- Deletion 22q11: spectrum of associated disorders. | Hay, BN. 2007. Semin Pediatr Neurol. 14: 136-9. PMID: 17980310
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SEC14L3 Antibody (E-1) | sc-515334 | 200 µg/ml | $322.00 | |||
SEC14L3 Antibody (E-1): m-IgG Fc BP-HRP Bundle | sc-528023 | 200 µg Ab; 10 µg BP | $361.00 | |||
SEC14L3 Antibody (E-1): m-IgG1 BP-HRP Bundle | sc-533396 | 200 µg Ab; 20 µg BP | $361.00 | |||
SEC14L3 Antibody (E-1) AC | sc-515334 AC | 500 µg/ml, 25% agarose | $424.00 | |||
SEC14L3 Antibody (E-1) HRP | sc-515334 HRP | 200 µg/ml | $322.00 | |||
SEC14L3 Antibody (E-1) FITC | sc-515334 FITC | 200 µg/ml | $336.00 | |||
SEC14L3 Antibody (E-1) PE | sc-515334 PE | 200 µg/ml | $349.00 | |||
SEC14L3 Antibody (E-1) Alexa Fluor® 488 | sc-515334 AF488 | 200 µg/ml | $364.00 | |||
SEC14L3 Antibody (E-1) Alexa Fluor® 546 | sc-515334 AF546 | 200 µg/ml | $364.00 | |||
SEC14L3 Antibody (E-1) Alexa Fluor® 594 | sc-515334 AF594 | 200 µg/ml | $364.00 | |||
SEC14L3 Antibody (E-1) Alexa Fluor® 647 | sc-515334 AF647 | 200 µg/ml | $364.00 | |||
SEC14L3 Antibody (E-1) Alexa Fluor® 680 | sc-515334 AF680 | 200 µg/ml | $364.00 | |||
SEC14L3 Antibody (E-1) Alexa Fluor® 790 | sc-515334 AF790 | 200 µg/ml | $364.00 |