Molecular structure of SDZ-201106 (±), (DPI-201106), CAS Number: 97730-95-5
SDZ-201106 (±), (DPI-201106) (CAS 97730-95-5)
See product citations (2)
Alternate Names:
4-[3-[4-(diphenylmethyl)-1-piperazinyl]-2-hydroxypropoxy]-1H-indole-2-carbonitrile
Application:
SDZ-201106 (±), (DPI-201106) is a positive inotropic and calcium sensitizing agent
CAS Number:
97730-95-5
Purity:
≥98%
Molecular Weight:
466.60
Molecular Formula:
C29H30N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
SDZ-201106 (±), (DPI-201106) is a Diphenylpiperazinylindole derivative. Positive inotropic and calcium sensitizing agent. Increases action potential duration (APD) of heart muscle. DPI 201-106 may act to increase the probability of the open state of the Na+ channel, thus increasing the force of the contraction. Used to study mechanisms of restoring the myofibrillar Ca2+ sensitivity and myosin enzymatic activity in diseased human hearts. Has both electron-donor and electron-acceptor activity.
SDZ-201106 (±), (DPI-201106) (CAS 97730-95-5) References
- Mg-ATPase and Ca+ activated myosin AtPase activity in ventricular myofibrils from non-failing and diseased human hearts--effects of calcium sensitizing agents MCI-154, DPI 201-106, and caffeine. | Okafor, C., et al. 2003. Mol Cell Biochem. 245: 77-89. PMID: 12708747
- Fatty acid replacements in a fatty acid auxotroph of Escherichia coli. | Silbert, DF., et al. 1968. J Bacteriol. 95: 1658-65. PMID: 4870280
- Role of arachidonic acid in stimulation of hexose transport by human polymorphonuclear leukocytes. | Bass, DA., et al. 1980. Proc Natl Acad Sci U S A. 77: 5125-9. PMID: 6776534
- In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. | Fernández-Repollet, E., et al. 1982. J Histochem Cytochem. 30: 466-70. PMID: 6804558
- The inotropic agents DPI 201-106 and BDF 9148 differentially affect potassium currents of guinea-pig ventricular myocytes. | Amos, GJ. and Ravens, U. 1994. Naunyn Schmiedebergs Arch Pharmacol. 350: 426-33. PMID: 7845480
- Delta 8 desaturation in vivo of deuterated eicosatrienoic acid by mouse liver. | Schenck, PA., et al. 1996. Lipids. 31: 593-600. PMID: 8784739
- A possible role of the redox interactions in the dual, activatory and inhibitory, action of DPI 201-106 on the potential-dependent Na+ channels. | Marinov, BS. 1997. Membr Cell Biol. 10: 707-15. PMID: 9231369
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SDZ-201106 (±), (DPI-201106), 25 mg | sc-201072 | 25 mg | $67.00 | |||
SDZ-201106 (±), (DPI-201106), 100 mg | sc-201072A | 100 mg | $217.00 | |||
SDZ-201106 (±), (DPI-201106), 250 mg | sc-201072B | 250 mg | $490.00 |