Scopoline (CAS 487-27-4)
QUICK LINKS
Scopoline is a compound utilized in various research disciplines, including organic chemistry and plant biochemistry. It serves as an intermediate in the biosynthesis of tropane alkaloids, which are natural compounds found in certain plants. In plant biochemistry, Scopoline is studied for its role in the metabolic pathways that lead to the production of scopolamine and other related alkaloids. This research is important for understanding the evolution of chemical defense mechanisms in plants. Additionally, in synthetic organic chemistry, Scopoline is used as a starting material or reference compound in the synthesis of more complex molecules, providing insights into reaction mechanisms and chemical synthesis strategies. It is also involved in the study of enzyme-substrate interactions within the tropane alkaloid biosynthetic pathway.
Scopoline (CAS 487-27-4) References
- Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model. | Muhammad, T., et al. 2019. J Neuroimmune Pharmacol. 14: 278-294. PMID: 30478761
- The protective effect of metformin in scopolamine-induced learning and memory impairment in rats. | Aksoz, E., et al. 2019. Pharmacol Rep. 71: 818-825. PMID: 31382167
- Effect of zerumbone on scopolamine-induced memory impairment and anxiety-like behaviours in rats. | Jafarian, S., et al. 2019. Alzheimers Dement (N Y). 5: 637-643. PMID: 31687471
- Scopolamine, a Toxin-Induced Experimental Model, Used for Research in Alzheimer's Disease. | Chen, WN. and Yeong, KY. 2020. CNS Neurol Disord Drug Targets. 19: 85-93. PMID: 32056532
- Succinamide Derivatives Ameliorate Neuroinflammation and Oxidative Stress in Scopolamine-Induced Neurodegeneration. | Iqbal, S., et al. 2020. Biomolecules. 10: PMID: 32183056
- Walnut Oil Prevents Scopolamine-Induced Memory Dysfunction in a Mouse Model. | Liao, J., et al. 2020. Molecules. 25: PMID: 32252285
- Effect of Glycyrrhizic Acid on Scopolamine-Induced Cognitive Impairment in Mice. | Ban, JY., et al. 2020. Int Neurourol J. 24: S48-55. PMID: 32482057
- Neuroprotective Effect of Spice Oleoresins on Memory and Cognitive Impairment Associated with Scopolamine-Induced Alzheimer's Disease in Rats. | Rajashri, K., et al. 2020. ACS Omega. 5: 30898-30905. PMID: 33324798
- Studying the interaction of scopolamine with calf-thymus DNA: An in-vitro and in-silico approach and genotoxicity. | Ameen, F., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 265: 120391. PMID: 34571375
- Neuroprotective Effects of Black Pepper Cold-Pressed Oil on Scopolamine-Induced Oxidative Stress and Memory Impairment in Rats. | Mostafa, NM., et al. 2021. Antioxidants (Basel). 10: PMID: 34943096
- Cornuside ameliorates cognitive impairments in scopolamine induced AD mice: Involvement of neurotransmitter and oxidative stress. | Wang, ZX., et al. 2022. J Ethnopharmacol. 293: 115252. PMID: 35405255
- Attenuation of Scopolamine-Induced Amnesia via Cholinergic Modulation in Mice by Synthetic Curcumin Analogs. | Hussain, H., et al. 2022. Molecules. 27: PMID: 35458662
- Protective Effects of Dapsone on Scopolamine-Induced Memory Impairment in Mice: Involvement of Nitric Oxide Pathway. | Noroozi, N., et al. 2022. Dement Geriatr Cogn Dis Extra. 12: 43-50. PMID: 35611148
- Neuroprotective effects of total alkaloids fraction of Huperzia serrata on scopolamine-induced neurodegenerative animals. | Dang, TK., et al. 2023. Phytother Res. 37: 140-150. PMID: 36065796
- Atropine and Scopolamine in Maize Products from the Retail Stores in the Republic of Serbia. | Vuković, G., et al. 2022. Toxins (Basel). 14: PMID: 36136559
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Scopoline, 1 g | sc-481896 | 1 g | $175.00 | |||
Scopoline, 5 g | sc-481896A | 5 g | $575.00 |