SCAND1 Antibody (SCANH7G4): sc-81377
- SCAND1 Antibody (SCANH7G4) is a mouse monoclonal IgG1 SCAND1 antibody provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of SCAND1 of human origin
- recommended for detection of SCAND1 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SCAND1 Antibody (SCANH7G4). This work is in progress.
QUICK LINKS
SCAND1 Antibody (SCANH7G4) is a mouse monoclonal IgG1 antibody that detects SCAND1 protein of human origin by western blotting (WB) and immunoprecipitation (IP). Anti-SCAND1 antibody (SCANH7G4) is available as a non-conjugated format. SCAND1, also known as SCAN domain containing 1, RAZ1, or SDP1, is a crucial nuclear protein involved in transcription regulation, which is essential for controlling gene expression and cellular function. SCAND1 is predominantly expressed in tissues such as the kidney, thyroid, liver, prostate, and testis, highlighting its significance in various physiological processes. Structurally, SCAND1 features a SCAN box domain, a conserved motif that facilitates protein-protein interactions, although SCAND1 notably lacks the zinc finger motif found in many other SCAN domain-containing proteins. The SCAN box domain, approximately 60 amino acids in length, is integral to its role in mediating interactions with other proteins, including ZNF38, ZNF191, MZF-1, ZNF202, and PPARγ. These interactions suggest SCAND1 is involved in the transcriptional regulation of genes related to energy homeostasis and lipid metabolism, making SCAND1 a vital player in maintaining metabolic balance within the cell.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SCAND1 Antibody (SCANH7G4) References:
- The SCAN domain mediates selective oligomerization. | Schumacher, C., et al. 2000. J Biol Chem. 275: 17173-9. PMID: 10747874
- Identification of a novel SCAN box-related protein that interacts with MZF1B. The leucine-rich SCAN box mediates hetero- and homoprotein associations. | Sander, TL., et al. 2000. J Biol Chem. 275: 12857-67. PMID: 10777584
- Characterization of the SCAN box encoding RAZ1 gene: analysis of cDNA transcripts, expression, and cellular localization. | Sander, TL. and Morris, JF. 2002. Gene. 296: 53-64. PMID: 12383503
- SDP1 is a peroxisome-proliferator-activated receptor gamma 2 co-activator that binds through its SCAN domain. | Babb, R. and Bowen, BR. 2003. Biochem J. 370: 719-27. PMID: 12444922
- Structural components of SCAN-domain dimerizations. | Nam, K., et al. 2004. Proteins. 56: 685-92. PMID: 15281122
- The SCAN domain family of zinc finger transcription factors. | Edelstein, LC. and Collins, T. 2005. Gene. 359: 1-17. PMID: 16139965
- Spectroscopic characterization of the tumor antigen NY-REN-21 and identification of heterodimer formation with SCAND1. | Carneiro, FR., et al. 2006. Biochem Biophys Res Commun. 343: 260-8. PMID: 16540086
- Structure of the SCAN domain from the tumor suppressor protein MZF1. | Peterson, FC., et al. 2006. J Mol Biol. 363: 137-47. PMID: 16950398
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SCAND1 Antibody (SCANH7G4) | sc-81377 | 100 µg/ml | $339.00 |