Salvinorin B (CAS 92545-30-7)
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Salvinorin B is a natural compound that is a derivative of Salvinorin A, the primary component found in the plant Salvia divinorum. In research applications, Salvinorin B is often studied for its interaction with the kappa-opioid receptor (KOR), although it has a lower affinity for this receptor compared to Salvinorin A. Studies involving Salvinorin B focus on elucidating the structure-activity relationships within KOR ligands, which can lead to a better understanding of the receptor′s role in modulating perception and consciousness. Research on Salvinorin B also contributes to the field of natural product chemistry, where its structure is analyzed to understand the biosynthetic pathways of terpenoids. Furthermore, Salvinorin B is used as a starting point for the synthesis of novel compounds that can help in the study of opioid receptors and their physiological functions.
Salvinorin B (CAS 92545-30-7) References
- Determination of Salvinorin A in body fluids by high performance liquid chromatography-atmospheric pressure chemical ionization. | Schmidt, MS., et al. 2005. J Chromatogr B Analyt Technol Biomed Life Sci. 818: 221-5. PMID: 15734162
- Synthesis and in vitro pharmacological evaluation of salvinorin A analogues modified at C(2). | Béguin, C., et al. 2005. Bioorg Med Chem Lett. 15: 2761-5. PMID: 15869877
- Synthesis and in vitro pharmacological studies of new C(2) modified salvinorin A analogues. | Lee, DY., et al. 2005. Bioorg Med Chem Lett. 15: 3744-7. PMID: 15993589
- Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates. | Schmidt, MD., et al. 2005. Synapse. 58: 208-10. PMID: 16138318
- Antinociceptive and hypothermic effects of Salvinorin A are abolished in a novel strain of kappa-opioid receptor-1 knockout mice. | Ansonoff, MA., et al. 2006. J Pharmacol Exp Ther. 318: 641-8. PMID: 16672569
- Unambiguous NMR spectral assignments of salvinorin A. | Giner, JL., et al. 2007. Magn Reson Chem. 45: 351-4. PMID: 17351976
- Determination of salvinorin A and salvinorin B in Salvia divinorum-related products circulated in Japan. | Tsujikawa, K., et al. 2008. Forensic Sci Int. 180: 105-9. PMID: 18768273
- In vitro stability and metabolism of salvinorin A in rat plasma. | Tsujikawa, K., et al. 2009. Xenobiotica. 39: 391-8. PMID: 19280383
- Analyzing salvia divinorum and its active ingredient salvinorin a utilizing thin layer chromatography and gas chromatography/mass spectrometry. | Jermain, JD. and Evans, HK. 2009. J Forensic Sci. 54: 612-6. PMID: 19298461
- Direct analysis of Salvia divinorum leaves for salvinorin A by thin layer chromatography and desorption electrospray ionization multi-stage tandem mass spectrometry. | Kennedy, JH. and Wiseman, JM. 2010. Rapid Commun Mass Spectrom. 24: 1305-11. PMID: 20391602
- Development of an enzyme immunoassay using a monoclonal antibody against the psychoactive diterpenoid salvinorin A. | Paudel, MK., et al. 2013. J Nat Prod. 76: 1654-60. PMID: 23987562
- A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior. | Vardy, E., et al. 2015. Neuron. 86: 936-946. PMID: 25937170
- 22-azidosalvinorin A exhibits antidepressant-like effect in mice. | Fajemiroye, JO., et al. 2017. Eur J Pharmacol. 800: 96-106. PMID: 28219707
- Salvinorin A reduces neuropathic nociception in the insular cortex of the rat. | Coffeen, U., et al. 2018. Eur J Pain. 22: 311-318. PMID: 28975684
- Therapeutic Potential of Salvinorin A and Its Analogues in Various Neurological Disorders. | Cichon, J., et al. 2022. Transl Perioper Pain Med. 9: 452-457. PMID: 35959414
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Salvinorin B, 1 mg | sc-472910 | 1 mg | $156.00 | |||
Salvinorin B, 5 mg | sc-472910A | 5 mg | $676.00 | |||
Salvinorin B, 25 mg | sc-472910B | 25 mg | $2611.00 | |||
Salvinorin B, 100 mg | sc-472910C | 100 mg | $2091.00 |