Rotavirus capsid Antibody (0541): sc-69944
- Rotavirus capsid Antibody (0541) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against Rotavirus capsid
- recommended for detection of intact RRV, WA and bovine strains of Rotavirus origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Rotavirus capsid Antibody (0541). This work is in progress.
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Rotavirus capsid Antibody (0541) is a mouse monoclonal IgG2a antibody that detects Rotavirus protein by enzyme-linked immunosorbent assay (ELISA). Anti-Rotavirus capsid antibody (0541) plays a crucial role in studying rotavirus infections, which are a leading cause of severe gastroenteritis in infants and young children. The rotavirus capsid is composed of three concentric protein layers, with the outer layers, VP4 and VP7, being essential for virus entry into host cells. These proteins are vital for viral structural integrity and facilitate entry through direct membrane penetration or endocytosis. Understanding the rotavirus capsid structure provides insights into virus-host cell interactions and immune response evasion, which can inform vaccine and therapeutic strategy development. Rotavirus capsid (0541) monoclonal antibody serves as an invaluable tool for researchers investigating rotavirus pathogenesis and infection mechanisms.
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Rotavirus capsid Antibody (0541) References:
- Antibody-independent protection against rotavirus infection of mice stimulated by intranasal immunization with chimeric VP4 or VP6 protein. | Choi, AH., et al. 1999. J Virol. 73: 7574-81. PMID: 10438847
- Oral and intraperitoneal immunization with rotavirus 2/6 virus-like particles stimulates a systemic and mucosal immune response in mice. | Shuttleworth, G., et al. 2005. Arch Virol. 150: 341-9. PMID: 15578236
- Rotavirus capsid surface protein VP4-coated Fe(3)O(4) nanoparticles as a theranostic platform for cellular imaging and drug delivery. | Chen, W., et al. 2012. Biomaterials. 33: 7895-902. PMID: 22841921
- Substantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species Infection. | Yu, X., et al. 2015. Chembiochem. 16: 2176-81. PMID: 26250751
- Engineering and expression of a human rotavirus candidate vaccine in Nicotiana benthamiana. | Pêra, FF., et al. 2015. Virol J. 12: 205. PMID: 26626122
- Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6. | Cho, MJ., et al. 2016. J Immunol. 197: 1065-73. PMID: 27402694
- In Silico Characterization of Epitopes from Human Rotavirus VP7 Genotype G9 Design for Vaccine Development. | Jalilian, S., et al. 2019. Iran J Allergy Asthma Immunol. 18: 664-670. PMID: 32245310
- Spectroscopic analysis of the bacterially expressed head domain of rotavirus VP6. | Strachan, MS., et al. 2024. Biosci Rep. 44: PMID: 38592735
- Electron microscopy of tubular assemblies associated with naturally occurring bovine rotavirus. | Chasey, D. and Labram, J. 1983. J Gen Virol. 64 (Pt 4): 863-72. PMID: 6300306
- Deletion mapping of functional domains in the rotavirus capsid protein VP6. | Affranchino, JL. and González, SA. 1997. J Gen Virol. 78 (Pt 8): 1949-55. PMID: 9266993
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rotavirus capsid Antibody (0541) | sc-69944 | 100 µg/ml | $316.00 |