Ristocetin A sulfate CAS: 11140-99-1
MF: C95H110N8O44•H2SO4
MW: 2,165.9
An antibiotic with platelet aggregation activity.

Ristocetin A sulfate (CAS 11140-99-1)

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Alternate Names: Ristocetin •sulfate, Ristomycin III•sulfate
Application: Ristocetin A sulfate is an antibiotic with platelet aggregation activity
CAS Number: 11140-99-1
Purity: >95%
Molecular Weight: 2,165.9
Molecular Formula: C95H110N8O44•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ristocetin A is an antibiotic that belongs to the class III glycopeptides. The compound has activity against gram-positive and gram-negative bacteria, and can be used in chromatography. Ristocetin A is structurally related to the glycopeptide antibiotics Teicoplanin (sc-208419) and vancomycin. Additionally, Ristocetin A has platelet aggregating activity and has been used in platelet aggregation studies. Studies have demonstrated that Ristocentin A dimerizes and creates two binding sites for cell wall peptides. We supply the Ristocetin A sulfate form.


References

1. Van Rooyen, C.E., et al. 1958. Can Med Assoc J. 79: 723-725. PMID: 13585306
2. Howard, M.A. and Firkin, B.G. 1971. Thromb Diath Haemorrh. 26: 362-369. PMID: 5316292
3. Kuwahara, S. and Chambers, W.T. 1978. Experientia. 34: 532-534. PMID: 565300
4. Gasper, M.P., et al. 1996. Anal. Chem. 68: 2501-2514. PMID: 8694258
5. Cho, Y.R., et al. 1996. Chem. Biol. 3: 207-215. PMID: 8807847
6. Ilisz, I., et al. 2006. J Sep Sci. 29: 1305-1321. PMID: 16894775
7. Nahoum, V., et al. 2009. Acta Crystallogr. D Biol. Crystallogr. 65: 832-838. PMID: 19622867

Physical State :
Solid
Derived From :
Amycolatopsis sp.
Solubility :
Soluble in water, methanol and DMSO.
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00076121
SMILES :
CC1C(C(CC(O1)OC2C3C(=O)NC(C4=CC(=CC(=C4C5=C(C=CC(=C5)C(C(=O)N3)NC(=O)C6C7=CC(=C(C(=C7)OC8=CC=C2C=C8)OC9C(C(C(C(O9)COC1C(C(C(C(O1)C)O)O)O)O)O)OC1C(C(C(C(O1)CO)O)O)OC1C(C(C(CO1)O)O)O)OC1=CC=C(C=C1)C(C1C(=O)NC(C2=CC(=C(C(=C2)O)C)OC2=C(C=CC(=C2)C(C(=O)N1)N)O)C(=O)N6)O)O)OC1C(C(C(C(O1)CO)O)O)O)O)C(=O)OC)N)O.OS(=O)(=O)O

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Certificate of Analysis

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