RIP3 Antibody (Rippy-3): sc-56228
- RIP3 Antibody (Rippy-3) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
- raised against full length RIP3 of human origin
- recommended for detection of RIP3 of mouse, rat and human origin by WB, IP and ELISA
- See RIP3 (B-2): sc-374639 for RIP3 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for RIP3 Antibody (Rippy-3). This work is in progress.
QUICK LINKS
RIP3 Antibody (Rippy-3) is a mouse monoclonal IgG1 antibody that detects RIP3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). RIP3 plays a crucial role in the regulation of programmed cell death, specifically in the process of necroptosis, which is a form of regulated necrosis that can occur when apoptosis is inhibited. RIP3 is primarily located in the cytoplasm, where RIP3 interacts with various signaling pathways to mediate cell death in response to specific stimuli, such as tumor necrosis factor (TNF) signaling. RIP3′s cytoplasmic localization enables rapid response to cellular stress and initiates necroptotic signaling cascades, thereby influencing cell fate decisions in both normal physiological processes and pathological conditions, such as inflammation and cancer. Additionally, RIP3 forms complexes with other proteins, including receptor-interacting protein 1 (RIP1) and mixed lineage kinase domain-like protein (MLKL), which are essential for the execution of necroptosis. Anti-RIP3 antibody (Rippy-3) serves as an invaluable tool for researchers studying cell death mechanisms and their implications in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RIP3 Antibody (Rippy-3) | sc-56228 | 50 µg/0.5 ml | $322.00 |