RBMS1 Antibody (73-K2): sc-101190

RBMS1 Antibody (73-K2) is a mouse monoclonal IgG1 kappa light chain antibody that detects RBMS1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-RBMS1 antibody (73-K2) is available as a non-conjugated format. RBMS1, also known as RNA binding motif, single stranded interacting protein 1, YC1, MSSP (c-Myc single strand binding protein), SCR2 (suppressor of Cdc2 with RNA binding motif), MSSP-1, MSSP-2, or MSSP-3, plays a crucial role in cellular processes by binding to single-stranded DNA and RNA, which is essential for gene regulation and stability. RBMS1 is predominantly localized in the nucleus and is expressed in tissues such as the lung, placenta, and heart, with peak expression during the G1 to S transition phase of the cell cycle, highlighting RBMS1′s importance in cell cycle regulation. RBMS1 contains two RNA recognition motifs, RNP1-A and RNP1-B, which are critical for binding nucleic acids, and specifically interacts with the catalytic subunit of DNA polymerase α, enhancing activity in vitro. Multiple isoforms of RBMS1, resulting from alternative splicing, further underscore the complexity of function and regulation in cellular processes.

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RBMS1 Antibody (73-K2) References:

1. MSSP, a protein binding to an origin of replication in the c-myc gene, interacts with a catalytic subunit of DNA polymerase alpha and stimulates its polymerase activity.  |  Niki, T., et al. 2000. FEBS Lett. 475: 209-12. PMID: 10869558
2. RNA-binding protein RBMS3 is expressed in activated hepatic stellate cells and liver fibrosis and increases expression of transcription factor Prx1.  |  Fritz, D. and Stefanovic, B. 2007. J Mol Biol. 371: 585-95. PMID: 17586524
3. Molecular cloning of MSSP-2, a c-myc gene single-strand binding protein: characterization of binding specificity and DNA replication activity.  |  Takai, T., et al. 1994. Nucleic Acids Res. 22: 5576-81. PMID: 7838710
4. SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins.  |  Kanaoka, Y. and Nojima, H. 1994. Nucleic Acids Res. 22: 2687-93. PMID: 8041632
5. Identification and cDNA cloning of single-stranded DNA binding proteins that interact with the region upstream of the human c-myc gene.  |  Negishi, Y., et al. 1994. Oncogene. 9: 1133-43. PMID: 8134115
6. Cloning and characterization of the genomic DNA of the human MSSP genes.  |  Haigermoser, C., et al. 1996. Nucleic Acids Res. 24: 3846-57. PMID: 8871567

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-RBMS1 Antibody (73-K2) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-RBMS1 Antibody (73-K2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

RBMS1 Antibody (73-K2) Specifications

Alternate Product Name: RBMS1

Product Clone Name: 73-K2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-404

Epitope Target: RBMS1

Epitope Species: human

Product Reactivity/Detection: RBMS1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for RBMS1 Antibody (73-K2): N/A