Molecular structure of (R)-(+)-Bay K 8644, CAS Number: 98791-67-4
(R)-(+)-Bay K 8644 (CAS 98791-67-4)
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Alternate Names:
(4R)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester
Application:
(R)-(+)-Bay K 8644 is an L-type calcium channel protein blocker
CAS Number:
98791-67-4
Molecular Weight:
356.30
Molecular Formula:
C16H15F3N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(R)-(+)-Bay K 8644 is a L-type calcium channel protein blocker with negative inotropic effects. (R)-(+)-Bay K 8644 is an enantiomer showing opposite effects to the racemate (±)-Bay K 8644 (sc-203324) and and (S)-(−)-Bay K8644 (sc-203525). Intracerebroventricular administration of this enantiomer has no effect on motor function in mice, whereas (−)-BAY-K-8644 impairs rotarod and motor activity, an effect that is blocked by (+)-BAY-K-8644.
(R)-(+)-Bay K 8644 (CAS 98791-67-4) References
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- Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Cav 1.1 by Dihydropyridine Compounds*. | Gao, S. and Yan, N. 2021. Angew Chem Int Ed Engl. 60: 3131-3137. PMID: 33125829
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Inhibitor of:
Calcium Channel Protein.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(R)-(+)-Bay K 8644, 1 mg | sc-364594B | 1 mg | $102.00 | |||
(R)-(+)-Bay K 8644, 10 mg | sc-364594 | 10 mg | $266.00 | |||
(R)-(+)-Bay K 8644, 50 mg | sc-364594A | 50 mg | $1087.00 |