(R)-Indoxacarb (CAS 185608-75-7)

(R)-Indoxacarb, a member of the oxadiazine class of chemicals, serves as a pesticide extensively employed in the agricultural industry to manage pests, particularly lepidopteran insects, notorious for causing substantial crop damage. The compound has demonstrated exceptional efficacy against these pests while exhibiting low toxicity towards non-target organisms. Its efficacy and safety have undergone thorough examination, establishing it as a vital component in pest management strategies implemented worldwide. Regulatory agencies in various countries, including the United States, Canada, and Australia, have approved its usage. The mechanism of action for (R)-Indoxacarb involves inhibiting sodium channels in the nervous system of insects, consequently disrupting nerve impulses and inducing paralysis, ultimately leading to the insect′s demise. Its selectivity towards insect sodium channels and minimal activity on mammalian channels contribute to its reputation as a safe and effective pesticide. (R)-Indoxacarb has been thoroughly evaluated to minimize its impact on non-target organisms, such as mammals, birds, and fish. It exhibits rapid metabolism and excretion, preventing environmental accumulation. Furthermore, studies indicate no significant effects on soil microorganisms or plant growth caused by the compound. These findings reinforce its favorable safety profile and environmental compatibility.