Quinolinic acid CAS: 89-00-9
MF: C7H5NO4
MW: 167.1
A matabolite of tryptophan and a putative NMDA receptor agonist.

Quinolinic acid (CAS 89-00-9)

Quinolinic acid | CAS 89-00-9 is rated 5.0 out of 5 by 1.
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Alternate Names: Pyridine-2,3-dicarboxylic acid
Application: Quinolinic acid is a matabolite of tryptophan and a putative NMDA receptor agonist
CAS Number: 89-00-9
Purity: 99%
Molecular Weight: 167.1
Molecular Formula: C7H5NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Quinolinic acid is a metabolite of tryptophan that acts as a putative NMDA receptor agonist.


References

1. Perkins, M.N. and Stone, T.W. 1981. Eur. J. Pharmacol. 72: 411-412. PMID: 6268428
2. Peet, M.J., et al. 1987. Neuroscience. 22: 563-571. PMID: 2823176

Physical State :
Solid
Solubility :
Soluble in water (partly), alkalies, dilute aqueous base, DMSO, and alcohol (slightly).
Storage :
Store at 4° C
Melting Point :
188-190° C (lit.)(dec.)
Boiling Point :
425.04° C at 760 mmHg (Predicted)
Density :
1.55 g/cm3 (Predicted)
Refractive Index :
n20D 1.63 (Predicted)
IC50 :
Glutamate receptor ionotropic, AMPA: IC50 > 0.1 mM (rat); Glutamate NMDA receptor: IC50 = 0.1 mM (rat)
pK Values :
pKa: 2.52 (Predicted), pKb: 5.12 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
US7967250
PubChem CID :
1066
Merck Index :
14: 8073
MDL Number :
MFCD00006295
EC Number :
201-874-8
Beilstein Registry :
137110
SMILES :
C1=CC(=C(N=C1)C(=O)O)C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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Quinolinic acid (CAS 89-00-9)  Product Citations

See how others have used Quinolinic acid (CAS 89-00-9). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 23548271  Sahm, F. et al. 2013. Cancer Res. -.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Col n Col n-Gonz lez AL; et al. (PubMed ID: 26343296) determined that Quinolinic acid can contirbute to neuro degeneration in rat brain synaptosomes. -SCBT Publication Review
Date published: 2015-03-29
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