Quinidine Antibody (504): sc-57992

Quinidine Antibody (504) is a mouse monoclonal IgG1 antibody that detects Quinidine in non-species reactive samples through enzyme-linked immunosorbent assay (ELISA). Quinidine, a class I antiarrhythmic agent derived from the bark of the cinchona tree, plays a crucial role in managing cardiac arrhythmias by blocking fast inward sodium currents, which decreases the phase 0 depolarization of the cardiac action potential and prolongs the QT interval on the electrocardiogram. This modulation of cardiac action potential is vital for maintaining a stable heart rhythm and preventing potentially life-threatening arrhythmias. Additionally, Quinidine interacts with various ion channels, including the tetrodotoxin-sensitive sodium current and calcium currents, as well as potassium rectifier currents, which further underscores Quinidine′s importance in cardiac electrophysiology. Quinidine (504) antibody serves as an essential tool for researchers studying the pharmacological effects of Quinidine and its interactions within the cardiovascular system, providing insights into therapeutic applications and potential side effects, such as inhibition of cytochrome P450 enzyme 2D6, which can lead to increased blood levels of other medications.