PSPH Antibody (3G12): sc-69704
- PSPH Antibody (3G12) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
- raised against full length recombinant PSPH of human origin
- recommended for detection of PSPH of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PSPH Antibody (3G12). This work is in progress.
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SEE ALSO...
PSPH Antibody (3G12) is a mouse monoclonal IgG1 antibody that detects phosphoserine phosphatase (PSPH) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). PSPH is a crucial enzyme composed of 225 amino acids that plays a vital role in the biosynthesis of serine, catalyzing the final and irreversible step of hydrolyzing O-phosphoserine to produce serine from carbohydrates. This process is essential not only for protein and nucleotide synthesis but also for cell signaling pathways that influence various physiological functions. PSPH shows high expression in periventricular neural progenitors in the embryonic brain, where PSPH is believed to facilitate neural stem cell proliferation, a critical aspect of brain development. Furthermore, deficiencies in PSPH have been linked to significant health issues, including pre- and postnatal growth retardation and moderate psychomotor retardation in humans, highlighting PSPH′s essential role in normal development and function. Anti-PSPH antibody (3G12) serves as an invaluable tool for researchers investigating the intricate mechanisms of serine metabolism and its implications in developmental biology and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSPH Antibody (3G12) | sc-69704 | 50 µg/0.5 ml | $322.00 |