Proteinase K [EC 3.4.21.64] (CAS 39450-01-6)
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Alternate Names:
Proteinase K [EC 3.4.21.64] is also known as Endopeptidase K.
Application:
Proteinase K [EC 3.4.21.64] is a stable and highly reactive serine protease from Tritirachium album.
CAS Number:
39450-01-6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Proteinase K [EC 3.4.21.64] is a stable and highly reactive serine protease enzyme belonging to the subtilisin family. It contains two disulfide bridges and one free Cys near the active site His. Proteinase K [EC 3.4.21.64] has an active-site catalytic triad (Asp39-His69-Ser224). It hydrolyzes peptide amides and catalyzes the reaction of keratin hydrolysis, as well as other proteins with substilisin-like specificity. Originally sourced from the mold Tritirachium album Limber, Proteinase K [EC 3.4.21.64] is also formerly known as the previous designations EC 3.4.4.16 and EC 3.4.21.14.
Proteinase K [EC 3.4.21.64] (CAS 39450-01-6) References
- Stromelysin 1, neutrophil collagenase, and collagenase 3 do not play major roles in a model of chondrocyte mediated cartilage breakdown. | Kozaci, LD., et al. 1998. Mol Pathol. 51: 282-6. PMID: 10193524
- A flow cytometry method for rapid detection and enumeration of total bacteria in milk. | Gunasekera, TS., et al. 2000. Appl Environ Microbiol. 66: 1228-32. PMID: 10698799
- Streptococcus thermophilus 580 produces a bacteriocin potentially suitable for inhibition of Clostridium tyrobutyricum in hard cheese. | Mathot, AG., et al. 2003. J Dairy Sci. 86: 3068-74. PMID: 14594223
- Immunomodulatory effects of polysaccharides produced by Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1. | Makino, S., et al. 2006. J Dairy Sci. 89: 2873-81. PMID: 16840603
- Insight derived from molecular dynamics simulation into substrate-induced changes in protein motions of proteinase K. | Tao, Y., et al. 2010. J Biomol Struct Dyn. 28: 143-58. PMID: 20645649
- Protein dynamics and motions in relation to their functions: several case studies and the underlying mechanisms. | Yang, LQ., et al. 2014. J Biomol Struct Dyn. 32: 372-93. PMID: 23527883
- Kinetic characterization of Channa striatus muscle sarcoplasmic and myofibrillar protein hydrolysates. | Ghassem, M., et al. 2014. J Food Sci Technol. 51: 467-75. PMID: 24587521
- Measuring protein structural changes on a proteome-wide scale using limited proteolysis-coupled mass spectrometry. | Schopper, S., et al. 2017. Nat Protoc. 12: 2391-2410. PMID: 29072706
- Staphylococcus aureus biofilm removal by targeting biofilm-associated extracellular proteins. | Shukla, SK. and Rao, TS. 2017. Indian J Med Res. 146: S1-S8. PMID: 29205189
- A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia. | Henrich, MT., et al. 2018. Acta Neuropathol Commun. 6: 39. PMID: 29747690
- DNA Extraction from Keratin and Chitin. | Campos, PF. and Gilbert, MTP. 2019. Methods Mol Biol. 1963: 57-63. PMID: 30875044
- Isolation, Characterization and Amino Acid Composition of a Bacteriocin Produced by Bacillus methylotrophicus Strain BM47. | Tumbarski, Y., et al. 2018. Food Technol Biotechnol. 56: 546-552. PMID: 30923451
- Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy. | Shahnawaz, M., et al. 2020. Nature. 578: 273-277. PMID: 32025029
- Magnetic proteinase K reactor as a new tool for reproducible limited protein digestion. | Slováková, M., et al. 2008. Bioconjug Chem. 19: 966-72. PMID: 18335999
Inhibitor of:
α-defensin 5.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Proteinase K [EC 3.4.21.64], 5 mg | sc-473603 | 5 mg | $40.00 | |||
Proteinase K [EC 3.4.21.64], 25 mg | sc-473603A | 25 mg | $100.00 | |||
Proteinase K [EC 3.4.21.64], 50 mg | sc-473603B | 50 mg | $153.00 | |||
Proteinase K [EC 3.4.21.64], 100 mg | sc-473603C | 100 mg | $203.00 | |||
Proteinase K [EC 3.4.21.64], 1 g | sc-473603D | 1 g | $850.00 |