Prostaglandin A2-d4 (CAS 201608-18-6)
Alternate Names:
Medullin-d4
CAS Number:
201608-18-6
Molecular Weight:
338.48
Molecular Formula:
C20H26D4O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Contains four deuterium atoms at the 3, 3′, 4, and 4′ positions and is intended for use as an internal standard for the quantification of PGA2 by GC- or LC- mass spectrometry. A naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammalsand has low biological potency in most bioassays, but does show some antiviral/antitumor activity.1 At a 25 µM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase.2 It has also been shown to act as a vasodilator with natriuretic properties.3
Prostaglandin A,[object Object],-d,[object Object], (CAS 201608-18-6) References
1 Fukushima, M., Kato, T., Narumiya, S., et al. Prostaglandin A and J: Antitumor and antiviral prostaglandins. Adv Prostaglandin Thromboxane Leukot Res 19 415-418 (1989). 2 Hitomi, M., Shu, J., Strom, D., et al. Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation. J Biol Chem 271 9376-9383 (1996). 3 Frolich, J.C., Sweetman, B.J., Carr, K., et al. Assessment of the levels of PGA2 in human plasma by gas chromatography-mass spectrometry. Prostaglandins 10 185-195 (1975).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prostaglandin A2-d4, 50 µg | sc-224213 | 50 µg | $43.00 | |||
Prostaglandin A2-d4, 100 µg | sc-224213A | 100 µg | $81.00 |