Prenalterol (CAS 57526-81-5)
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Prenalterol is a compound studied in the context of its beta-adrenergic agonist activity, particularly its interaction with beta-1 adrenergic receptors in cardiac tissue. Research on prenalterol focuses on its potential to enhance myocardial contractility, making it a subject of interest for understanding the modulation of heart function. It serves as a useful tool in experimental cardiology to probe the intricacies of adrenergic receptor signaling pathways and their role in the regulation of heart rate and force of contraction. Additionally, prenalterol is used to examine the receptor subtype selectivity of beta-adrenergic agonists and to investigate the cardiac responses to adrenergic stimulation. This research provides insights that are instrumental in the design of new compounds with improved selectivity and efficacy for beta-adrenergic receptors.
Prenalterol (CAS 57526-81-5) References
- Effects of prenalterol on beta adrenergic responsiveness and receptors in the cerebral cortex of the rat. | Ordway, GA. and Frazer, A. 1988. Neuropharmacology. 27: 529-36. PMID: 2839793
- Increase of cyclic AMP in subcellular fractions of rat heart muscle after beta-adrenergic stimulation: prenalterol and isoprenaline caused different distribution of bound cyclic AMP. | Aass, H., et al. 1988. J Mol Cell Cardiol. 20: 847-60. PMID: 2852724
- The lack of a pronounced preference of prenalterol for the beta-l-adrenoceptor subtype. | Rohm, N., et al. 1980. Naunyn Schmiedebergs Arch Pharmacol. 315: 85-8. PMID: 6113550
- beta 1-Adrenoceptors mediating relaxation of the guinea-pig trachea: experiments with prenalterol, a beta 1-selective adrenoceptor agonist. | Johansson, U. and Waldeck, B. 1981. J Pharm Pharmacol. 33: 353-6. PMID: 6115005
- In vitro studies on the cardiac activity of prenalterol with reference to use in congestive heart failure. | Kenakin, TP. and Beek, D. 1982. J Pharmacol Exp Ther. 220: 77-85. PMID: 6118432
- The metabolic disposition of the selective beta 1-adrenoceptor agonist prenalterol in mice, rats, dogs, and humans. | Hoffmann, KJ., et al. 1982. Drug Metab Dispos. 10: 173-9. PMID: 6124405
- The haemodynamic effects of intravenous prenalterol and ouabain in conscious dogs. | Ek, L., et al. 1982. Acta Med Scand Suppl. 659: 39-52. PMID: 6127899
- Intrinsic sympathomimetic activity of the partial agonist prenalterol in relation to beta adrenoceptor interaction in various tissues, in vitro. | Mattsson, H., et al. 1983. J Pharmacol Exp Ther. 224: 654-61. PMID: 6131123
- Relative efficacy of prenalterol and pirbuterol for beta-1 adrenoceptors: measurement of agonist affinity by alteration of receptor number. | Kenakin, TP. and Beek, D. 1984. J Pharmacol Exp Ther. 229: 340-5. PMID: 6143816
- Effects of in vivo treatment with isoprenaline or prenalterol on beta-adrenoceptor mechanisms in the heart and soleus muscle of the cat. | Hedberg, A., et al. 1984. Naunyn Schmiedebergs Arch Pharmacol. 325: 251-8. PMID: 6145101
- Influence of heart rate on the effects of prenalterol on regional myocardial blood flow and function during coronary stenosis in dogs. | Berdeaux, A., et al. 1984. Br J Pharmacol. 83: 203-10. PMID: 6148979
- The measurement of the relative efficacy of agonists by selective potentiation of tissue responses: studies with isoprenaline and prenalterol in cardiac tissue. | Kenakin, TP. and Beek, D. 1984. J Auton Pharmacol. 4: 153-9. PMID: 6208197
- Characterization of mechanical effects and beta-adrenoceptor binding of prenalterol in rat myocardium. | Aass, H., et al. 1983. Acta Pharmacol Toxicol (Copenh). 53: 3-11. PMID: 6310958
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prenalterol, 5 mg | sc-280023A | 5 mg | $145.00 | |||
Prenalterol, 25 mg | sc-280023 | 25 mg | $525.00 |