Polyquaternium 1 (CAS 75345-27-6)
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Polyquaternium-1 is a polymeric quaternary ammonium compound used extensively in the field of materials science and industrial applications. In research, it is explored for its antimicrobial properties, particularly when incorporated into hydrogels, coatings, and other materials that require biocidal functionality. Studies also delve into the interaction of Polyquaternium-1 with various substrates to understand its adhesion properties and how it can be used to enhance the stability of colloidal systems. Researchers are interested in its potential as a flocculant in water treatment processes, where its charged nature aids in the aggregation of particulate matter for easier removal. Additionally, Polyquaternium-1 is investigated for its conditioning properties, which are of interest in the formulation of personal care products. The compound′s ability to form a film on surfaces is utilized in research aimed at creating protective barriers, which can be beneficial in various industrial and consumer applications.
Polyquaternium 1 (CAS 75345-27-6) References
- Aspects of the antimicrobial mechanisms of action of a polyquaternium and an amidoamine. | Codling, CE., et al. 2003. J Antimicrob Chemother. 51: 1153-8. PMID: 12697638
- Identification of genes involved in the susceptibility of Serratia marcescens to polyquaternium-1. | Codling, CE., et al. 2004. J Antimicrob Chemother. 54: 370-5. PMID: 15231770
- Comparison of toxicological profiles of benzalkonium chloride and polyquaternium-1: an experimental study. | Labbé, A., et al. 2006. J Ocul Pharmacol Ther. 22: 267-78. PMID: 16910868
- The preservative polyquaternium-1 increases cytoxicity and NF-kappaB linked inflammation in human corneal epithelial cells. | Paimela, T., et al. 2012. Mol Vis. 18: 1189-96. PMID: 22605930
- The effect of contact lens materials on disinfection activity of polyquaternium-1 and myristamidopropyl dimethylamine multipurpose solution against Staphylococcus aureus. | Shoff, ME., et al. 2012. Eye Contact Lens. 38: 374-8. PMID: 23111451
- [Preservatives in ophthalmology]. | Messmer, EM. 2012. Ophthalmologe. 109: 1064-70. PMID: 23179809
- Effects of Polyhexamethylene Biguanide and Polyquaternium-1 on Phospholipid Bilayer Structure and Dynamics. | Horner, IJ., et al. 2015. J Phys Chem B. 119: 10531-42. PMID: 26239890
- Dendritiform Keratopathy Associated with Exposure to Polyquarternium-1, a Common Ophthalmic Preservative. | Matoba, AY., et al. 2016. Ophthalmology. 123: 451-6. PMID: 26686962
- Acute Corneal Toxicity of Combined Antiglaucoma Topical Eyedrops. | Mohamed, YH., et al. 2016. Curr Eye Res. 41: 1326-1330. PMID: 27002346
- Polyquaternium-1-Associated Dendritiform Keratopathy. | Verkade, A. and Matoba, AY. 2019. Cornea. 38: 502-503. PMID: 30702469
- Ocular Surface Disease with BAK preserved Travoprost and Polyquaternium 1(Polyquad) preserved Travoprost. | Kumar, S., et al. 2019. Rom J Ophthalmol. 63: 249-256. PMID: 31687627
- Activity of Deposited Lysozyme on Contemporary Soft Contact Lenses Exposed to Differing Lens Care Systems. | Heynen, M., et al. 2021. Clin Ophthalmol. 15: 1727-1733. PMID: 33935489
- Antiviral effect of multipurpose contact lens disinfecting solutions against coronavirus. | Yasir, M., et al. 2022. Cont Lens Anterior Eye. 45: 101513. PMID: 34465537
- Generic benzalkonium chloride-preserved travoprost eye drops are not identical to the branded polyquarternium-1-preserved travoprost eye drop: Effect on cultured human conjunctival goblet cells and their physicochemical properties. | Hedengran, A., et al. 2022. Acta Ophthalmol. 100: 819-827. PMID: 35527390
- Multipurpose Lens Care Systems and Silicone Hydrogel Contact Lens Wettability: A Systematic Review. | Capote-Puente, R., et al. 2022. Eye Contact Lens. 48: 356-361. PMID: 36002943
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Polyquaternium 1, 100 mg | sc-476677 | 100 mg | $343.00 |