Poly(cytidylic-inosinic) acid potassium salt (CAS 26301-44-0)
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Poly(cytidylic-inosinic) acid potassium salt is a synthetic polynucleotide that is extensively used in molecular biology research. This compound serves as an analogue of double-stranded RNA and is utilized in the study of RNA structure and function. It provides insights into the mechanisms of RNA interference, a process of gene silencing that is critical for regulating gene expression. Furthermore, researchers employ poly(cytidylic-inosinic) acid potassium salt to investigate the activation of immune responses, particularly the stimulation of toll-like receptors that recognize RNA patterns characteristic of viral genetic material. It is also instrumental in the study of the innate immune system′s response to viral infections. Additionally, this polynucleotide is used in the exploration of RNA-protein interactions, which is fundamental to understanding the complexities of post-transcriptional regulation within cells.
Poly(cytidylic-inosinic) acid potassium salt (CAS 26301-44-0) References
- Persistence of double-stranded RNA in insect hemolymph as a potential determiner of RNA interference success: evidence from Manduca sexta and Blattella germanica. | Garbutt, JS., et al. 2013. J Insect Physiol. 59: 171-8. PMID: 22664137
- Synergistic induction of interferon α through TLR-3 and TLR-9 agonists identifies CD21 as interferon α receptor for the B cell response. | Kim, D. and Niewiesk, S. 2013. PLoS Pathog. 9: e1003233. PMID: 23516365
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Poly(cytidylic-inosinic) acid potassium salt, 5 mg | sc-215724 | 5 mg | $153.00 | |||
Poly(cytidylic-inosinic) acid potassium salt, 10 mg | sc-215724A | 10 mg | $293.00 |