Molecular structure of (±)-4′-Hydroxy Mephenytoin-d3, CAS Number: 1173022-56-4
(±)-4′-Hydroxy Mephenytoin-d3 (CAS 1173022-56-4)
Alternate Names:
5-Ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione-d3; (±)-5-Ethyl-(4-hydroxyphenyl)-3-methylhydantoin-d3; p-Hydroxymephenytoin-d3
Application:
(±)-4′-Hydroxy Mephenytoin-d3 is a deuterated CYP2C19 metabolite of Mephenytoin
CAS Number:
1173022-56-4
Molecular Weight:
237.27
Molecular Formula:
C12H11D3N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(±)-4′-Hydroxy Mephenytoin-d3 is the deuterated form of a Mephenytoin metabolite produced by CYP2C19 processing. The compound is metabolized in the liver by the cytochrome P450 enzyme system. It is used in scientific research to study the metabolism and effects of Mephenytoin.
(±)-4′-Hydroxy Mephenytoin-d3 (CAS 1173022-56-4) References
- Differential time- and NADPH-dependent inhibition of CYP2C19 by enantiomers of fluoxetine. | Stresser, DM., et al. 2009. Drug Metab Dispos. 37: 695-8. PMID: 19144769
- A sensitive and specific CYP cocktail assay for the simultaneous assessment of human cytochrome P450 activities in primary cultures of human hepatocytes using LC-MS/MS. | Pillai, VC., et al. 2013. J Pharm Biomed Anal. 74: 126-32. PMID: 23245243
- Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in CYP2C9 and CYP2C19. | Devarajan, S., et al. 2019. Drug Metab Dispos. 47: 425-435. PMID: 30745309
- Identification and functional validation of novel pharmacogenomic variants using a next-generation sequencing-based approach for clinical pharmacogenomics. | Siamoglou, S., et al. 2022. Pharmacol Res. 176: 106087. PMID: 35033648
- Identification of mephenytoin metabolites in the dog. | Karlaganis, G., et al. 1980. Drug Metab Dispos. 8: 173-7. PMID: 6104582
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)-4′-Hydroxy Mephenytoin-d3, 2.5 mg | sc-217056 | 2.5 mg | $357.00 |