PLEKHJ1 Antibody (H-10): sc-514666
- PLEKHJ1 Antibody (H-10) is a mouse monoclonal IgG2a κ PLEKHJ1 antibody provided at 200 µg/ml
- raised against amino acids 1-56 mapping at the N-terminus of PLEKHJ1 of human origin
- PLEKHJ1 Antibody (H-10) is recommended for detection of PLEKHJ1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-PLEKHJ1 Antibody (H-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for PLEKHJ1 Antibody (H-10) for WB applications. These reagents are now offered in bundles with PLEKHJ1 Antibody (H-10) (see ordering information below).
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PLEKHJ1 Antibody (H-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects PLEKHJ1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PLEKHJ1 Antibody (H-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PLEKHJ1, also known as pleckstrin homology domain containing, family J member 1 or guanine nucleotide-releasing protein x, is a 149 amino acid phosphoprotein characterized by the presence of a pleckstrin homology domain, which plays a crucial role in mediating protein-protein interactions and cellular signaling pathways. PLEKHJ1 is predominantly expressed in the testis and liver, where PLEKHJ1 is involved in various cellular processes, including signal transduction and cytoskeletal organization. The gene encoding PLEKHJ1 is located on human chromosome 19, a region known for its high gene density and association with several genetic disorders, including Peutz-Jeghers syndrome and spinocerebellar ataxia type 6. Understanding PLEKHJ1 function is essential, as PLEKHJ1 may provide insights into cellular dynamics and potential implications in disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PLEKHJ1 Antibody (H-10) References:
- Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). | LaPoint, SF., et al. 2000. Adv Anat Pathol. 7: 307-21. PMID: 10976909
- Search for the second Peutz-Jeghers syndrome locus: exclusion of the STK13, PRKCG, KLK10, and PSCD2 genes on chromosome 19 and the STK11IP gene on chromosome 2. | Buchet-Poyau, K., et al. 2002. Cytogenet Genome Res. 97: 171-8. PMID: 12438709
- The DNA sequence and biology of human chromosome 19. | Grimwood, J., et al. 2004. Nature. 428: 529-35. PMID: 15057824
- Immunogenetics of killer cell immunoglobulin-like receptors. | Parham, P. 2005. Mol Immunol. 42: 459-62. PMID: 15607799
- A novel CADASIL-causing mutation in a stroke patient. | Vikelis, M., et al. 2007. Swiss Med Wkly. 137: 323-5. PMID: 17629811
- Integrated genomic and expression profiling in mantle cell lymphoma: identification of gene-dosage regulated candidate genes. | Schraders, M., et al. 2008. Br J Haematol. 143: 210-21. PMID: 18699851
- Analysis of gene order conservation in eukaryotes identifies transcriptionally and functionally linked genes. | Dávila López, M., et al. 2010. PLoS One. 5: e10654. PMID: 20498846
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PLEKHJ1 Antibody (H-10) | sc-514666 | 200 µg/ml | $322.00 | |||
PLEKHJ1 Antibody (H-10): m-IgG Fc BP-HRP Bundle | sc-526385 | 200 µg Ab; 10 µg BP | $361.00 | |||
PLEKHJ1 Antibody (H-10): m-IgG2a BP-HRP Bundle | sc-546615 | 200 µg Ab; 10 µg BP | $361.00 | |||
PLEKHJ1 Antibody (H-10) AC | sc-514666 AC | 500 µg/ml, 25% agarose | $424.00 | |||
PLEKHJ1 Antibody (H-10) HRP | sc-514666 HRP | 200 µg/ml | $322.00 | |||
PLEKHJ1 Antibody (H-10) FITC | sc-514666 FITC | 200 µg/ml | $336.00 | |||
PLEKHJ1 Antibody (H-10) PE | sc-514666 PE | 200 µg/ml | $349.00 | |||
PLEKHJ1 Antibody (H-10) Alexa Fluor® 488 | sc-514666 AF488 | 200 µg/ml | $364.00 | |||
PLEKHJ1 Antibody (H-10) Alexa Fluor® 546 | sc-514666 AF546 | 200 µg/ml | $364.00 | |||
PLEKHJ1 Antibody (H-10) Alexa Fluor® 594 | sc-514666 AF594 | 200 µg/ml | $364.00 | |||
PLEKHJ1 Antibody (H-10) Alexa Fluor® 647 | sc-514666 AF647 | 200 µg/ml | $364.00 | |||
PLEKHJ1 Antibody (H-10) Alexa Fluor® 680 | sc-514666 AF680 | 200 µg/ml | $364.00 | |||
PLEKHJ1 Antibody (H-10) Alexa Fluor® 790 | sc-514666 AF790 | 200 µg/ml | $364.00 |