Plasmodium falciparum Antibody (MPFM-55A): sc-65732

Plasmodium falciparum Antibody (MPFM-55A) is a mouse monoclonal IgM antibody that detects histidine-rich protein II (HRP2) of Plasmodium falciparum origin by western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). Anti-HRP2 antibody (MPFM-55A) is available in a non-conjugated form, making it suitable for various experimental applications. HRP2 plays a crucial role in malaria pathogenesis, as HRP2 is secreted by the parasite into the bloodstream during infection, allowing for parasite detection in patients. HRP2 serves as a biomarker for diagnosing P. falciparum malaria, enabling timely and effective treatment. Accurate measurement of HRP2 levels can significantly impact patient outcomes, especially in regions where malaria is endemic. The P. falciparum genome, rich in adenine and thymine bases, encodes HRP2 among its over 5,300 genes, highlighting HRP2′s significance in parasite biology and potential as a target for therapeutic intervention.

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Plasmodium falciparum Antibody (MPFM-55A) References:

1. Plasmodium falciparum: in vitro interactions of artemisinin with amodiaquine, pyronaridine, and chloroquine.  |  Gupta, S., et al. 2002. Exp Parasitol. 100: 28-35. PMID: 11971651
2. The plastid DNA of the malaria parasite Plasmodium falciparum is replicated by two mechanisms.  |  Williamson, DH., et al. 2002. Mol Microbiol. 45: 533-42. PMID: 12123462
3. A proteomic view of the Plasmodium falciparum life cycle.  |  Florens, L., et al. 2002. Nature. 419: 520-6. PMID: 12368866
4. The apicoplast: a plastid in Plasmodium falciparum and other Apicomplexan parasites.  |  Foth, BJ. and McFadden, GI. 2003. Int Rev Cytol. 224: 57-110. PMID: 12722949
5. Neutral lipid synthesis and storage in the intraerythrocytic stages of Plasmodium falciparum.  |  Vielemeyer, O., et al. 2004. Mol Biochem Parasitol. 135: 197-209. PMID: 15110461
6. Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins.  |  Ting, LM., et al. 2005. J Biol Chem. 280: 9547-54. PMID: 15576366
7. Identification of putative Plasmodium falciparum mefloquine resistance genes.  |  Jeffress, M. and Fields, S. 2005. Mol Biochem Parasitol. 139: 133-9. PMID: 15664648
8. Gene sequence tags from Plasmodium falciparum genomic DNA fragments prepared by the 'genease' activity of mung bean nuclease.  |  Reddy, GR., et al. 1993. Proc Natl Acad Sci U S A. 90: 9867-71. PMID: 8234327
9. The dynamics of Plasmodium falciparum blood-stage infection.  |  McKenzie, FE. and Bossert, WH. 1997. J Theor Biol. 188: 127-40. PMID: 9299316

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Plasmodium falciparum Antibody (MPFM-55A) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Plasmodium falciparum Antibody (MPFM-55A) Specifications

Alternate Product Name: Plasmodium falciparum

Product Clone Name: MPFM-55A

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: mouse IgM

Amino Acids:

Epitope Target: Plasmodium falciparum

Epitope Species: Plasmodium falciparum

Product Reactivity/Detection: histidine rich protien II (HRP2)

Species Reactivity/Detection: Plasmodium falciparum

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, ELISA

Vialing Information: Each vial contains 100 µg IgM in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Plasmodium falciparum Antibody (MPFM-55A): N/A