Pinolenic Acid (CAS 16833-54-8)
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Pinolenic acid is a polyunsaturated fatty acid primarily found in the seeds of pine trees. It is of particular interest in nutritional and metabolic research due to its role in lipid metabolism and potential impact on satiety and weight management. Studies involving pinolenic acid focus on its effect on the release of hunger-suppressing hormones, such as cholecystokinin and glucagon-like peptide-1, which are key to understanding the regulation of food intake. Additionally, pinolenic acid is being explored for its influence on the lipid profile of the blood, where it may affect levels of low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Research in the field of plant physiology also examines pinolenic acid for its contribution to the defensive resins of pine trees, which can offer insights into plant defense mechanisms and ecological interactions.
Pinolenic Acid (CAS 16833-54-8) References
- Pinolenic acid inhibits human breast cancer MDA-MB-231 cell metastasis in vitro. | Chen, SJ., et al. 2011. Food Chem. 126: 1708-15. PMID: 25213948
- Preparation of highly purified pinolenic acid from pine nut oil using a combination of enzymatic esterification and urea complexation. | No, da S., et al. 2015. Food Chem. 170: 386-93. PMID: 25306361
- Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases. | Christiansen, E., et al. 2015. Br J Nutr. 113: 1677-88. PMID: 25916176
- Pinolenic Acid Downregulates Lipid Anabolic Pathway in HepG2 Cells. | Lee, AR. and Han, SN. 2016. Lipids. 51: 847-55. PMID: 27084371
- Pinolenic Acid in Structured Triacylglycerols Exhibits Superior Intestinal Lymphatic Absorption As Compared to Pinolenic Acid in Natural Pine Nut Oil. | Chung, MY., et al. 2017. J Agric Food Chem. 65: 1543-1549. PMID: 28198188
- Enzymatic Synthesis of Structured Monogalactosyldiacylglycerols Enriched in Pinolenic Acid. | Kim, J., et al. 2018. J Agric Food Chem. 66: 8079-8085. PMID: 29998729
- Preparation of Pinolenic Acid Concentrates from Pine Nut Oil Fatty Acids by Solvent Fractionation. | Chung, MY., et al. 2018. J Oleo Sci. 67: 1373-1379. PMID: 30404957
- Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cells. | Zhang, J., et al. 2019. Eur J Pharmacol. 861: 172618. PMID: 31430456
- Investigation of Modulatory Effect of Pinolenic Acid (PNA) on Inflammatory Responses in Human THP-1 Macrophage-Like Cell and Mouse Models. | Chen, SJ., et al. 2020. Inflammation. 43: 518-531. PMID: 31776889
- A review of the functional effects of pine nut oil, pinolenic acid and its derivative eicosatrienoic acid and their potential health benefits. | Baker, EJ., et al. 2021. Prog Lipid Res. 82: 101097. PMID: 33831456
- Anti-inflammatory and immunoregulatory effects of pinolenic acid in rheumatoid arthritis. | Takala, R., et al. 2022. Rheumatology (Oxford). 61: 992-1004. PMID: 34080609
- Effect of pinolenic acid on oxidative stress injury in HepG2 cells induced by H2O2. | Zhao, Y., et al. 2021. Food Sci Nutr. 9: 5689-5697. PMID: 34646537
- Pinolenic acid exhibits anti-inflammatory and anti-atherogenic effects in peripheral blood-derived monocytes from patients with rheumatoid arthritis. | Takala, R., et al. 2022. Sci Rep. 12: 8807. PMID: 35614190
- The Beneficial Effects of Pine Nuts and Its Major Fatty Acid, Pinolenic Acid, on Inflammation and Metabolic Perturbations in Inflammatory Disorders. | Takala, R., et al. 2023. Int J Mol Sci. 24: PMID: 36674687
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pinolenic Acid, 0.5 mg | sc-205437 | 0.5 mg | $40.00 | |||
Pinolenic Acid, 5 mg | sc-205437B | 5 mg | $104.00 | |||
Pinolenic Acid, 10 mg | sc-205437C | 10 mg | $135.00 | |||
Pinolenic Acid, 25 mg | sc-205437D | 25 mg | $238.00 |